The major connector is the most vital component critically subjected to maximal stress concentration due to various forces acting on it. The main requirement of a major connector is its resistance to deformation by occlusal stresses. This resistance to deformation is a direct consequence of the rigidity of the major connector. Thus rigidity of the major connector is paramount to resist flexing and torquing forces that could be transmitted to the abutment teeth and other structures as destructive forces. The commonly used major connectors for the mandibular arch are lingual bar and lingual plate. In the present study, the deflection of various major connector designs due to occlusal load is assessed by finite element method. They have been analyzed through finite element models. The differences in the deflection behaviour of mandibular major connector used in Kennedy's Class I, Class II, Class III, and Class IV edentulous situations have been compared. A CT scan of human edentulous mandible was taken and each section from symphysis to condylar region was projected on a graph paper and three-dimensional volumes were created from connected successive profiles to define the final solid geometry of cortical bone. Six framework models with different mandibular major connectors, lingual bar and lingual plate for Kennedy's Class I, Class II, Class III, and Class IV situations were created. The three dimensional finite element models corresponding to the geometric model were generated using Ansys's pre-processor. The model was assigned material properties. A vertical biting force of 20 N was applied. The results showed that the maximum deflection was seen in the saddle area when compared to other areas, i.e., major connector and the occlusal rest regions. The lingual bar in Kennedy's Class III situation and lingual plate in Kennedy's Class IV situation showed the least deflection when compared to Class I and Class II (distal extensions) situations. Lingual plate is more rigid major connector than lingual bar.
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http://dx.doi.org/10.1007/s13191-012-0191-0 | DOI Listing |
Materials (Basel)
December 2024
Key Laboratory of New Technology for Construction of Cities in Mountain Area, School of Civil Engineering, Chongqing University, Chongqing 400045, China.
High-strength bolt connectors, known for their robust strength and ease of disassembly, are suitable not only for the construction of new steel-concrete composite beams but also for reinforcing existing composite or steel beams. Static push-out tests were performed on nine specimens to examine their shear behavior. The primary failure mode was observed at the steel-concrete interface, characterized by the tensile-shear failure of the bolt and localized crushing of the concrete beneath the bolt.
View Article and Find Full Text PDFbioRxiv
December 2024
Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Tailed bacteriophages with double-stranded DNA genomes (class ) play an important role in the evolution of bacterial pathogenicity, both as carriers of genes encoding virulence factors and as the main means of horizontal transfer of mobile genetic elements (MGEs) in many bacteria, such as . The pathogenicity islands (SaPIs), including SaPI1, are a type of MGEs are that carry a variable complement of genes encoding virulence factors. SaPI1 is mobilized at high frequency by "helper" bacteriophages, such as 80α, leading to packaging of the SaPI1 genome into virions made from structural proteins supplied by the helper.
View Article and Find Full Text PDFEur Arch Otorhinolaryngol
December 2024
Department of Otorhinolaryngology and Head-Neck Surgery, Dr. B. C. Roy Multispeciality Medical Research Centre, Indian Institute of Technology, Kharagpur, West Bengal, India.
Objective: To ascertain the effect of coronavirus (COVID-19) pandemic on routine (non-COVID) Otolaryngology and Head-Neck Surgery (ORL-HNS) turnover in a tertiary-care teaching institute, utilizing the cumulated, finalized dataset one year after the pandemic ceased to be a "public health emergency of international concern".
Methodology: In this retrospective analysis, annual routine turnover in the ORL-HNS categories (otology, rhinology/skull-base, head-neck/airway, emergency, miscellaneous) for the COVID-period (2020-21) were individually compared with pre-COVID (2017-19) data. Subsequently, categorical turnovers, along with the major surgeries in each category, were compared trimester-wise in the COVID-period.
ACS Omega
October 2024
DMMT, University of Brescia, Viale Europa 11, Brescia 25121, Italy.
The d(GGCGCC) palindrome is encountered in several oncogenic and retroviral sequences. In order to target it, we previously designed several oligopeptide derivatives of the mitoxantrone and ametantrone anticancer intercalators. These have two arms with a cationic side-chain in the major groove, each destined to bind along each strand O/N of the two successive guanine bases (G1-G2/G1'-G2') upstream from the central anthraquinone intercalation site.
View Article and Find Full Text PDFJ Biol Chem
November 2024
Department of Microbiology and Molecular Genetics, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA. Electronic address:
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