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[The influence of nooclerin on the structure of sleep disturbances in children with tension headaches].
Zh Nevrol Psikhiatr Im S S Korsakova
February 2020
Russian national research Pirogov's University medical Ministry of health of Russia, Moscow, Russia.
Aim: To study the effects of nooclerin (deanol aceglumate) on the structure of sleep disturbances in children with tension-type headache (TTH).
Material And Methods: A blind randomized placebo-controlled study of the efficacy of nooclerin (deanol aceglumate), prescribed for 2 months to prevent TTH, was carried out. The study included 60 patients (30 boys and 30 girls), aged 9-16 years, with TTH.
[Possibilities of preventive treatment of tension-type headache in children and adolescents].
Zh Nevrol Psikhiatr Im S S Korsakova
November 2018
Pirogov Russian National Research Medical University, Moscow, Russia.
Aim: To study clinical characteristics mechanisms and pathogenesis of the tension-type headache (TTH) in children and adolescents treated with nooclerin.
Material And Methods: The blind randomized placebo-controlled study of the efficacy of nooclerin (deanol aceglumate) indicated during 2 months as a preventive treatment of TTH was performed. Forty patients (15 male and 25 female), aged 9-16 years, were randomized into two equal groups to receive either nooclerin or placebo.
[Deanol aceglumate (nooclerin): clinical/pharmacological aspects and relevance in clinical practice].
Zh Nevrol Psikhiatr Im S S Korsakova
July 2014
Experiments on mice with streptozotocin-induced diabetes mellitus and stress-induced erosive ulcerous damage of the mucous membrane of stomach showed evidence of the preventive activity of deanol aceglumate in the course of peroral introduction at a dose of 250 mg/kg per 24 h during 4 days. This effect is accompanied by activation of the peristalsis of bowels and by an increase in the blood flow in the wall of stomach.
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