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ZnCl2-catalyzed chemoselective cascade reactions of enaminones with 2-furylcarbinols: a versatile process for the synthesis of cyclopenta[b]pyrrole derivatives. | LitMetric

ZnCl2-catalyzed chemoselective cascade reactions of enaminones with 2-furylcarbinols: a versatile process for the synthesis of cyclopenta[b]pyrrole derivatives.

Chem Commun (Camb)

Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Department of Chemistry, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, People's Republic of China.

Published: February 2014

A highly efficient ZnCl2-catalyzed cascade reaction of enaminones with 2-furylcarbinols under mild reaction conditions has been developed. This methodology offers a chemo- and diastereo-selective access to functionalized cyclopenta[b]pyrrole derivatives in good to excellent yields.

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Source
http://dx.doi.org/10.1039/c3cc49191aDOI Listing

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