A 64-year old man presented to A&E with a 24 h history of persistent hypothermia and increasing confusion. His medical history included congestive heart failure, hypertension and intermittent claudication secondary to distal abdominal aortic occlusion. Examination revealed profound hypothermia-31°C, bilateral reduced power in the lower limbs and no palpable peripheral pulses. Initial blood tests revealed a metabolic acidosis with hyperlactactaemia, neutrophilia and deranged electrolytes. CT scan of the abdomen revealed extensive thromboemobolic disease of the abdominal arterial tree and diagnosed acute mesenteric ischaemia. The patient was taken to theatre where an emergency laparotomy demonstrated a perforated duodenum, which was subsequently patched, followed immediately by an axillofemoral bypass with subsequent femoral-femoral crossover. Sadly, the patient passed away shortly after completion of surgery.
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http://dx.doi.org/10.1136/bcr-2013-202774 | DOI Listing |
Front Neurol
January 2025
Department of Neurology, Hubei No. 3 People's Hospital of Jianghan University, Wuhan, China.
Background: Therapeutic hypothermia improves outcomes in experimental stroke models, especially after ischemia-reperfusion injury. In recent years, the safety and efficacy of hypothermia combining thrombolysis or mechanical thrombectomy have attracted widespread attention. The primary objective of the study was to evaluate the effectiveness and safety of hypothermia by combining reperfusion therapy in acute ischemic stroke patients.
View Article and Find Full Text PDFJ Cardiothorac Vasc Anesth
January 2025
Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA; Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA. Electronic address:
Objective: To determine the impact of hematocrit on adverse neurologic events after acute type A aortic dissection (ATAAD) repair under deep hypothermic circulatory arrest.
Design: Retrospective study of consecutive aortic surgeries from 2010 to 2021.
Setting: Single institution.
Front Neurol
January 2025
Department of Neurosurgical Intensive Care Unit, Henan Provincial People's Hospital, Zhengzhou, China.
Background: The effect of targeted temperature management (TTM) combined with decompressive craniectomy (DC) on poor-grade aneurysmal subarachnoid hemorrhage (aSAH) has not been previously addressed in the literature. This study aims to investigate the therapeutic outcomes of the combination of TTM and DC in patients with poor-grade aSAH.
Methods: This study represents a secondary analysis of the Multicenter Clinical Research on Targeted Temperature Management of Poor-grade Aneurysmal Subarachnoid Hemorrhage (High-Quality TTM for PaSAH), a multicenter prospective study conducted in China.
BMC Cardiovasc Disord
January 2025
Department of Cardiovascular Surgery, The Second Xiangya Hospital of Central South University, Changsha, 410011, China.
Background: As hypothermic circulatory arrest (HCA) is being more frequently induced in patients undergoing aortic arch surgery, its safety at different degrees has become a crucial area of study. The aim of this study was to assess the surgical outcomes of mild hypothermic circulatory arrest (MI-HCA) during aortic arch surgery.
Methods: Acute type A aortic dissection (ATAAD) patients who underwent total arch replacement (TAR) and frozen elephant trunk (FET) surgery between January 2014 and December 2023 were enrolled in this study.
Am J Transl Res
December 2024
Department of Anesthesiology, Huai'an First People's Hospital Huai'an, Jiangsu, China.
Objective: To evaluate the clinical effect of a subspecialty standardized temperature management process in a hybrid surgery for treating acute aortic dissection.
Methods: From January 2020 to June 2021, 102 patients who underwent hybrid surgery for acute aortic dissection in the Department of Cardiovascular Surgery at the Huai'an First People's Hospital were selected as the control group, receiving routine temperature maintenance measures. From August 2021 to November 2022, 105 similar patients from the same hospital were enrolled in the experimental group, where a subspecialty standardized temperature management process was implemented.
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