Crohn's Disease is a chronic, idiopathic, transmural inflammatory disease affecting predominantly distal ileum, the common presentation include stricture and fistula formation. Free perforation in the peritoneal cavity is rare. To study the presentation and management of Crohn's perforation. A retrospective study of 9 cases of perforative peritonitis later diagnosed due to Crohn's disease on histopathological examination. Among the 9 patients, 8 were males and 1 was female. The ages of the patients ranged from 30 to 58 years, with mean age of 41.8 years. 6 patients were in the age group of 30-45 years. 8 patients were not known to be suffering from Crohn's. Resection followed by anastomosis was done in 4 cases including the case of known Crohn's, while resection follwed by end illeostomy with mucous fistula was done in remaining cases. Resected specimens were sent for histopathological examination in all cases. Though Crohn's perforation is rare it should be kept in mind when dealing with single or multiple perforation of the small intestine even in the developing countries. Though the number of cases in our series are too few to come to a conclusion, we found that illeostomy sems a prudent alternative to traditional resection anastomosis.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585532PMC
http://dx.doi.org/10.1007/s12262-012-0453-4DOI Listing

Publication Analysis

Top Keywords

crohn's perforation
12
crohn's disease
8
histopathological examination
8
crohn's resection
8
resection anastomosis
8
crohn's
7
cases
5
perforation uncommon
4
uncommon indian
4
indian population
4

Similar Publications

Background/aims: Radial incision and cutting (RIC) is an alternative dilation method for stenosis of the lower gastrointestinal tract. However, its safety and efficacy for the small intestine requiring balloon-assisted enteroscopy (BAE) remain limited. Therefore, this pilot study aimed to evaluate the safety and efficacy of RIC using BAE.

View Article and Find Full Text PDF

BACKGROUND Crohn disease is a chronic inflammatory bowel disease known for causing fistulous tracts, abscesses, and bowel perforation. Enterohepatic fistulas, a rare but significant complication, are scarcely reported. This article presents the case of a hepatic abscess due to an enterohepatic fistula in a patient with long-term Crohn disease and reviews the existing literature on this phenomenon.

View Article and Find Full Text PDF

Ocular Manifestations of IBD: Pathophysiology, Epidemiology, and Iatrogenic Associations of Emerging Treatment Strategies.

Biomedicines

December 2024

Department of Gastroenterology, The Royal Wolverhampton NHS Trust, Wolverhampton WV10 0QP, UK.

Inflammatory bowel disease (IBD) is a complex, multisystemic disease and is associated with ocular pathology in 4-12% of patients. In general, ocular disease affects Crohn's patients more frequently than those with ulcerative colitis. Episcleritis and uveitis are the most common presentations, with episcleritis often correlating with IBD flares, whereas uveitis presents independently of IBD activity and, in some cases, may even alert clinicians to a new diagnosis of IBD.

View Article and Find Full Text PDF
Article Synopsis
  • - Ameboma is a rare complication from invasive amebiasis caused by a specific intestinal protozoan, leading to tumor-like inflammatory masses in the lower right abdomen.
  • - Symptoms can vary but often include intestinal obstruction and gastrointestinal bleeding, and while imaging techniques like CT and ultrasound can reveal colonic masses, biopsy remains the most reliable way to diagnose ameboma.
  • - Treatment generally involves targeting the protozoan causing the infection, with surgery being necessary for severe cases like intestinal obstruction or other serious complications.
View Article and Find Full Text PDF

Computed Tomography and Magnetic Resonance Enterography: From Protocols to Diagnosis.

Diagnostics (Basel)

November 2024

Department of Diagnostic Radiology, IRCCS Fondazione San Gerardo dei Tintori, Via Pergolesi 33, 20900 Monza, Italy.

Article Synopsis
  • - Both Magnetic Resonance Enterography (MRE) and Computed Tomography Enterography (CTE) are important imaging techniques used for diagnosing and treating inflammatory bowel disease (IBD), with CTE being favored in urgent situations like suspected complications.
  • - CTE provides rapid and precise imaging but involves exposure to ionizing radiation, while MRE avoids radiation and excels in evaluating the small intestine and perianal disease, making it ideal for patients requiring frequent monitoring or those who are pregnant.
  • - The review highlights the strengths and weaknesses of both imaging methods, aiming to inform about their technical aspects, benefits, limitations, and the specific findings they can reveal regarding IBD.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!