A 43-year-old man with a high-grade glioma involving the cerebellar nodulus showed a near-complete suppression of periodic alternating nystagmus (PAN) in the lateral decubitus position to either side. This positional modulation of PAN is consistent with suppression of the velocity storage mechanism by head position changes (tilt dumping) and is supportive of the role of the velocity storage mechanism in generating PAN.
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http://dx.doi.org/10.1097/WNO.0000000000000098 | DOI Listing |
Br J Sociol
January 2025
AAU Business School, Aalborg University, Aalborg, Denmark.
What is the relationship between legitimation and institutionalization? We take a fresh look at a more complex and nuanced landscape than has previously been documented. Our approach is to view legitimation and institutionalization as separate, though related, processes. We engage in theory building to develop a typology suggesting four different ways in which the social construction of reality can be achieved: instantiating (mutual causal emergence, coming into being), realizing (legitimating toward institutionalization), aspiring (legitimating from institutionalization) and missing (mutual causal suppression, unrealized potential).
View Article and Find Full Text PDFHIV Med
January 2025
Centre for Immunology and Vaccinology, Imperial College London, London, UK.
Introduction: The HIV/AIDS epidemic, with 85.6 million infections and 40.4 million AIDS-related deaths globally, remains a critical public health challenge.
View Article and Find Full Text PDFHandb Clin Neurol
January 2025
Centre for Chronobiology, Psychiatric Hospital of the University of Basel, Basel, Switzerland; Research Cluster Molecular and Cognitive Neurosciences, University of Basel, Basel, Switzerland; Department of Biomedicine, University of Basel, Basel, Switzerland.
The nonvisual effects of light in humans are mainly conveyed by a subset of retinal ganglion cells that contain the pigment melanopsin which renders them intrinsically photosensitive (= intrinsically photosensitive retinal ganglion cells, ipRGCs). They have direct connections to the main circadian clock in the suprachiasmatic nuclei (SCN) of the hypothalamus and modulate a variety of physiological processes, pineal melatonin secretion, autonomic functions, cognitive processes such as attention, and behavior, including sleep and wakefulness. This is because efferent projections from the SCN reach other hypothalamic nuclei, the pineal gland, thalamus, basal forebrain, and the brainstem.
View Article and Find Full Text PDFCrit Rev Oncol Hematol
January 2025
Department of Biology, Texas A&M University, College Station, TX, USA; Texas A&M Center for Biological Clocks Research. Electronic address:
Physiological processes such as the sleep-wake cycle, metabolism, hormone secretion, neurotransmitter release, sensory capabilities, and a variety of behaviors, including sleep, are controlled by a circadian rhythm adapted to 24-hour day-night periodicity. Disruption of circadian rhythm may lead to the risks of numerous diseases, including cancers. Several epidemiological and clinical data reveal a connection between the disruption of circadian rhythms and cancer.
View Article and Find Full Text PDFPolymers (Basel)
January 2025
Department of Materials and Applied Chemistry, College of Science and Technology, Nihon University, 1-8-14 Kandasurugadai, Chiyoda-ku, Tokyo 101-8308, Japan.
Calcified tissues in living organisms, such as bone, dentin, and enamel, often require surgical intervention for treatment. However, advances in regenerative medicine have increased the demand for materials to assist in regenerating these tissues. Among the various forms of calcium phosphate (CaP), tricalcium phosphate (TCP)-particularly its α-TCP form-stands out due to its high solubility and efficient calcium release, making it a promising candidate for bone regeneration applications.
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