Objectives: We describe a methodology for school-based sealant programs (SBSP) to estimate averted cavities, (i.e., difference in cavities without and with SBSP) over 9 years using a minimal data set.
Methods: A Markov model was used to estimate averted cavities. SBSP would input estimates of their annual attack rate (AR) and 1-year retention rate. The model estimated retention 2+ years after placement with a functional form obtained from the literature. Assuming a constant AR, SBSP can estimate their AR with child-level data collected prior to sealant placement on sealant presence, number of decayed/filled first molars, and age. We demonstrate the methodology with data from the Wisconsin SBSP. Finally, we examine how sensitive averted cavities obtained with this methodology is if an SBSP were to over or underestimate their AR or 1-year retention.
Results: Demonstrating the methodology with estimated AR (= 7 percent) and 1-year retention (= 92 percent) from the Wisconsin SBSP data, we found that placing 31,324 sealants averted 10,718 cavities. Sensitivity analysis indicated that for any AR, the magnitude of the error (percent) in estimating averted cavities was always less than the magnitude of the error in specifying the AR and equal to the error in specifying the 1-year retention rate. We also found that estimates of averted cavities were more robust to misspecifications of AR for higher- versus lower-risk children.
Conclusions: With Excel (Microsoft Corporation, Redmond, WA, USA) spreadsheets available upon request, SBSP can use this methodology to generate reasonable estimates of their impact with a minimal data set.
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http://dx.doi.org/10.1111/jphd.12047 | DOI Listing |
Br Dent J
December 2024
Peninsula Dental School, University of Plymouth, Plymouth, UK; School of Nursing and Midwifery, University of Plymouth, Plymouth, UK.
Aim The study aims to conduct economic evaluation of the Peninsula Dental Social Enterprise (PDSE) programme for people experiencing homelessness over an 18-month period, when compared to a hypothetical base-case scenario ('status quo').Methods A decision tree model was generated in TreeAge Pro Healthcare 2024. Benefit-cost analysis and cost-effectiveness analysis were performed using data informed by the literature and probabilistic sensitivity analysis (Monte Carlo simulation with 1,000 cycles).
View Article and Find Full Text PDFCureus
June 2024
Anaesthesiology, Hospital do Divino Espírito Santo de Ponta Delgada, EPE, Ponta Delgada , PRT.
Central venous catheter (CVC) insertion is a routine procedure in the management of critically ill patients. We report a clinical case of inadvertent placement of an internal jugular vein CVC into the right pleural cavity, despite employing clinical and imaging-based techniques to ensure proper catheter positioning. Infusion of fluids and vasopressors through this misplaced catheter led to hypertensive pleural effusion and subsequent cardiorespiratory arrest.
View Article and Find Full Text PDFPLoS One
July 2024
Apple Tree Institute of Biomedical Science, Apple Tree Medical Foundation, Goyang-si, Gyeonggi-do, Republic of Korea.
Chronic oral inflammation and biofilm-mediated infections drive diseases such as dental caries and periodontitis. This study investigated the anti-inflammatory and antibacterial potential of an ethanol extract from Astilbe chinensis inflorescence (GA-13-6) as a prominent candidate for natural complex substances (NCS) with therapeutic potential. In LPS-stimulated RAW 264.
View Article and Find Full Text PDFInt J Paediatr Dent
January 2025
Head, Oral Health Sciences Centre, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Background: Supervised toothbrushing (STB) significantly reduces the incidence and progression of dental caries. School years present a favorable age for introducing such healthy habits for a lifetime.
Aim: To estimate the cost-effectiveness of implementing a STB program in India in preventing dental caries incidence.
Egypt Heart J
May 2024
Department of Clinical Cardiology, Mohammed V Military Hospital, Rabat, Morocco.
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