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Epigenetics in 2013. DNA methylation and miRNA: key roles in systemic autoimmunity. | LitMetric

Epigenetics in 2013. DNA methylation and miRNA: key roles in systemic autoimmunity.

Nat Rev Rheumatol

Department of Rheumatology/Immunology, University of Michigan, 3007 BSRB, 109 Zina Pitcher Place, Ann Arbor, MI 48109-2200, USA.

Published: February 2014

AI Article Synopsis

Article Abstract

Several advances in 2013 have improved our understanding of how epigenetic mechanisms affect autoimmune disorders. Many new insights were made into the regulation of gene expression by DNA methylation in systemic lupus erythematosus. For rheumatoid arthritis, complex interrelationships between DNA methylation and microRNAs in regulating gene expression were described.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332710PMC
http://dx.doi.org/10.1038/nrrheum.2013.211DOI Listing

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