Limonoids from the leaves of Soymida febrifuga and their insect antifeedant activities.

Bioorg Med Chem Lett

Division of Natural Products Chemistry, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500 607, India. Electronic address:

Published: February 2014

Three new phragmalin-type limonoids (1-3) were isolated from the leaves of Soymida febrifuga together with thirteen known limonoids. The structures of these compounds were established on the basis of spectroscopic data. All these isolates were evaluated for their anti-feedant activities in tobacco caterpillar (Spodoptera litura) and castor semilooper (Achaea janata) using a no-choice laboratory bioassay. Among the tested, compounds 9 and 15 demonstrated the potent anti-feedant index (76.46 μg/cm(2), 66.61 μg/cm(2) against A. janata, and 61.69 μg/cm(2), 51.93 μg/cm(2)against S. litura).

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http://dx.doi.org/10.1016/j.bmcl.2013.12.077DOI Listing

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