Three new phragmalin-type limonoids (1-3) were isolated from the leaves of Soymida febrifuga together with thirteen known limonoids. The structures of these compounds were established on the basis of spectroscopic data. All these isolates were evaluated for their anti-feedant activities in tobacco caterpillar (Spodoptera litura) and castor semilooper (Achaea janata) using a no-choice laboratory bioassay. Among the tested, compounds 9 and 15 demonstrated the potent anti-feedant index (76.46 μg/cm(2), 66.61 μg/cm(2) against A. janata, and 61.69 μg/cm(2), 51.93 μg/cm(2)against S. litura).
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Bioorg Med Chem Lett
February 2014
Division of Natural Products Chemistry, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500 607, India. Electronic address:
Three new phragmalin-type limonoids (1-3) were isolated from the leaves of Soymida febrifuga together with thirteen known limonoids. The structures of these compounds were established on the basis of spectroscopic data. All these isolates were evaluated for their anti-feedant activities in tobacco caterpillar (Spodoptera litura) and castor semilooper (Achaea janata) using a no-choice laboratory bioassay.
View Article and Find Full Text PDFFood Chem Toxicol
November 2008
Pharmacology Division, Indian Institute of Chemical Technology, Uppal Road, Tarnaka, Hyderabad 500007, India.
There is increasing evidence that oxidative stress is implicated in pathogenesis of various diseases, including alcoholic liver injury. In the present study, we investigated the comparative protective effects of leaf, bark, root and root bark extracts of Soymida febrifuga (Roxb.) A.
View Article and Find Full Text PDFPak J Pharm Sci
July 2008
MGV's Pharmacy College, Department of Pharmacognosy, Panchavati, Nasik, Maharastra, India.
Soymida febrifuga (Meliaceae) dried leaflets (10 gm) were extracted with petroleum ether. Unsaponifiable matter quantitatively used for sample preparation, labeled as SF-U. Another 10 gm leaflet powder was extracted with methanol and quantitatively used for sample preparation labeled as SF-A.
View Article and Find Full Text PDFPhytother Res
July 2008
Pharmacology Division, Indian Institute of Chemical Technology, Uppal Road, Hyderabad 500007, India.
The present study was designed to evaluate the antioxidant and antimicrobial properties of hexane (LH), methanol (LM) and aqueous (LA) extracts of Soymida febrifuga (Maliaceae) leaves, which is a traditional folk medicine in India. No pharmacological evaluation of this plant (except antiplasmodial activity) has been reported to date. Antioxidant activity of different extracts was evaluated by DPPH free radical scavenging activity, taking total phenolic content (TPC) as an index.
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