Thrombotic events occurring in the course of celiac disease are frequently reported in the literature. The localization is often unusual, mainly affecting the hepatic veins. To our knowledge, this is the first report of intracardiac thrombosis occurring in a patient with celiac disease. A 32-year-old patient with celiac disease adhered poorly to his gluten-free diet. He suffered an ischemic stroke revealing an intracardiac thrombus, which, on radiological imaging, simulated a multiple myxoma. Histological examination of the resected tumor enabled the correct diagnosis. Biological findings revealed severe protein C and S deficiency. The patient improved with anticoagulant therapy and gluten-free diet.
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http://dx.doi.org/10.1016/j.jmv.2013.12.002 | DOI Listing |
Semin Immunol
March 2025
Celiac Disease Research Center, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
In celiac disease (CeD), dietary gluten serves as the driver for a comparatively well characterized small bowel mucosal immune response that generally results in small bowel mucosal villous atrophy and crypt hyperplasia along with a disease-specific transglutaminase 2 (TG2) targeting autoantibody response. Individuals with positive TG2 autoantibodies but normal small intestinal mucosal morphology are regarded at increased risk of developing CeD and represent patients with potential CeD. The removal of gluten from the diet leads to disappearance of the autoantibodies and normalization of the mucosal architecture in most cases.
View Article and Find Full Text PDFJ Endovasc Ther
March 2025
Department of Thoracic and Vascular Surgery, Linköping University Hospital, Linköping, Sweden.
Purpose: To demonstrate the feasibility of the physician-modified endovascular graft (PMEG) technique in acute aorta disease, even in cases with a previous PMEG requiring a new repair.
Technique: A 77-year-old man presented with an infectious native aortic aneurysm (INAA), which was treated with a PMEG containing fenestrations for the renal arteries and superior mesenteric artery (SMA). After 4 months, a new infectious aneurysm developed at the right renal hilum, which was treated by occluding the right renal artery with a vascular plug.
J Biomol Struct Dyn
March 2025
Department of Plant Molecular Biology and Bioinformatics, CPMB&B, TNAU, Coimbatore, India.
Barnyard millet () is a nutritionally superior grain and a rich source of dietary fiber, and protein. It helps in managing health and dietary issues such as malnutrition, diabetes, obesity, and celiac disease. Its low content of slowly digestible carbohydrates promotes a gradual release of glucose, helping to maintain stable blood glucose levels.
View Article and Find Full Text PDFAm J Gastroenterol
March 2025
Harvard Celiac Research Program, Harvard Medical School, Boston, Massachusetts, United States.
Objective: Determine contemporary rates of early mucosal recovery in children with celiac disease (CeD).
Methods: Multicenter retrospective cohort study in Canada and the United States. Children diagnosed with CeD between 2016 and 2021 who underwent a follow-up biopsy within 15 months of diagnosis were included.
Inflamm Res
March 2025
Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Objective: Severe steroid hyporesponsive asthma is a heterogeneous group of chronic inflammatory diseases characterized by irreversible airflow limitation, hyperresponsiveness, inflammation, and remodelling of the airways. Severe asthmatics account for more than 60% of asthma-related healthcare cost worldwide given they are hyporesponsive to corticosteroids and due to the absence of targeted treatment specifically for the T helper-17 (Th-17) high endotype. Hence, there is a clear unmet need to investigate other treatment options to control patients' symptoms.
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