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Presence of Fragmented Intratumoral Thrombosed Microvasculature in the Necrotic and Peri-Necrotic Regions on SWI Differentiates IDH Wild-Type Glioblastoma From IDH Mutant Grade 4 Astrocytoma.
J Magn Reson Imaging
January 2025
Department of Radiology, Fortis Memorial Research Institute, Gurugram, India.
Background: Isocitrate dehydrogenase (IDH) wild-type (IDH) glioblastomas (GB) are more aggressive and have a poorer prognosis than IDH mutant (IDH) tumors, emphasizing the need for accurate preoperative differentiation. However, a distinct imaging biomarker for differentiation mostly lacking. Intratumoral thrombosis has been reported as a histopathological biomarker for GB.
View Article and Find Full Text PDFClinical Efficacy of Ultrafast Dynamic Contrast-Enhanced MRI Using Compressed Sensing in Distinguishing Benign and Malignant Soft-Tissue Tumors.
Korean J Radiol
January 2025
Research Scientist, AIRS Medical Inc., Seoul, Republic of Korea.
Objective: To evaluate the clinical efficacy of ultrafast dynamic contrast-enhanced (DCE)-MRI using a compressed sensing (CS) technique for differentiating benign and malignant soft-tissue tumors (STTs) and to evaluate the factors related to the grading of malignant STTs.
Materials And Methods: A total of 165 patients (96 male; mean age, 61 years), comprising 111 with malignant STTs and 54 with benign STTs according to the 2020 WHO classification, underwent DCE-MRI with CS between June 2018 and June 2023. The clinical, qualitative, and quantitative parameters associated with conventional MRI were also obtained.
Editorial for "Development and Validation of a Deep Learning System to Differentiate HER2-Zero, HER2-Low, and HER2-Positive Breast Cancer Based on Dynamic Contrast-Enhanced MRI".
J Magn Reson Imaging
January 2025
Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, Utah, USA.
Chronological changes in etiology, pathological and imaging findings in primary liver cancer from 2001 to 2020.
Jpn J Clin Oncol
January 2025
Department of Pathology, Keio University School of Medicine, Tokyo, Japan.
Purpose: To achieve a historical perspective, the chronological changes in primary liver cancer over a 20-year period were investigated at a single institution, focusing on shifts in etiology and the impact on imaging and pathological findings using The Liver Imaging Reporting and Data System.
Materials And Methods: A retrospective study of surgically resected primary liver cancer in 680 patients from 2001 to 2020 resulted in 434 patients with 482 nodules being analyzed. Dynamic contrast-enhanced computed tomography imaging and the Liver Imaging Reporting and Data System 2018 classification were employed.
The value of multiparametric MRI radiomics and machine learning in predicting preoperative Ki-67 expression level in breast cancer.
BMC Med Imaging
January 2025
Department of Radiology, Suzhou Ninth People's Hospital, Ludang Street 2666#, Suzhou, Jiangsu, 215200, PR China.
Objective: This study was to develop a multi-parametric MRI radiomics model to predict preoperative Ki-67 status.
Materials And Methods: A total of 120 patients with pathologically confirmed breast cancer were retrospectively enrolled and randomly divided into a training set (n = 84) and a validation set (n = 36). Radiomic features were derived from both the intratumoral and peritumoral regions, extending 5 mm from the tumor boundary, using magnetic resonance imaging (MRI).
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