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Objectives: This study aims to explore the correlation between Pyridoxal 5'-Phosphate (PLP) levels and lipid profiles in adult individuals, utilizing data from the National Health and Nutrition Examination Survey (NHANES) database.

Methods: The research included individuals aged 20 years and above, extracted from the NHANES database, covering the period from 2005 to 2010. The primary objective was to scrutinize the relationship between PLP and lipid profiles.

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Background/objectives: Yacon syrup () has gained attention due to its high concentration of fructooligosaccharides (FOSs) and associated health benefits. This systematic review aimed to evaluate the effects of yacon syrup on metabolic parameters and intestinal health in humans over the last decade.

Methods: Following PRISMA guidelines, we conducted a systematic search in databases, including Medline (PubMed), Science Direct, Embase, Scopus, and SciELO, up to October 2024.

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Untargeted Metabolomics and Chemometrics Elucidate Dynamic Plasma Profile Changes Induced by Cocoa Shell in Female Rats.

Nutrients

February 2025

Food, Oxidative Stress and Cardiovascular Health (FOSCH) Research Group, Universidad Autónoma de Madrid, 28049 Madrid, Spain.

Objective: This study aimed to explore the effects of cocoa shell extract (CSE) supplementation on the plasma metabolome of female rats.

Methods: Female rats were supplemented with CSE (250 mg/kg/day) over seven days, and plasma samples were collected at baseline, day 4, and day 7 for untargeted metabolomic profiling using LC-ESI-QTOF.

Results: A total of 244 plasma metabolites were identified, while 180 were detected in the CSE.

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Clinical Evaluation of Spore Oil for Triglyceride Reduction: A Randomized, Double-Blind, Crossover Study.

Nutrients

February 2025

Beijing Key Laboratory of Functional Food from Plant Resources, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.

: spore oil (GLSO) is widely recognized for its notable medicinal and nutritional properties. This study aimed to systematically evaluate the efficacy and safety of GLSO extract in individuals with dyslipidemia. : In a randomized, double-blind, placebo-controlled trial, 110 participants were enrolled and randomly assigned to either the intervention group or the placebo group.

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: Understanding gene-diet interactions is crucial for establishing dietary guidelines for cardiovascular diseases (CVD). This study analyzed the interaction between dietary intake and six genome-wide association study (GWAS)-identified single nucleotide polymorphisms (SNP) associated with high-density lipoprotein (HDL) cholesterol levels and their impact on CVD risk. : A total of 68,806 participants in the Korean Genome and Epidemiology Study (KoGES) were analyzed.

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