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PM and hospitalizations through the emergency department in people with disabilities: a nationwide case-crossover study in South Korea.
Lancet Reg Health West Pac
December 2024
School of Biomedical Convergence Engineering, College of Information and Biomedical Engineering, Pusan National University, Yangsan, South Korea.
Background: Little is known about the impact of PM on people with disabilities. We aimed to explore the association between PM and hospitalization via the emergency department (ED admission) among people with disabilities, together with the attributable ED admission cases and costs.
Methods: We applied a time-stratified case-crossover design adjusting ozone, holiday, and temperature using seven years (2015-2021) of claim-based data on ED admissions from the Korean National Health Insurance Database.
Breathing orchestrates synchronization of sleep oscillations in the human hippocampus.
Proc Natl Acad Sci U S A
December 2024
Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611.
Nested sleep oscillations, emerging from asynchronous states in coordinated bursts, are critical for memory consolidation. Whether these bursts emerge intrinsically or from an underlying rhythm is unknown. Here, we show a previously undescribed respiratory-driven oscillation in the human hippocampus that couples with cardinal sleep oscillations.
View Article and Find Full Text PDFThis research study synthesizes research on applications of artificial intelligence (AI) to transform and improve quality of life for deaf and hard of hearing students. Twenty studies were analyzed, spanning domains including AI-enabled captioning, interpreters, personalized tutors, social robots, and assistive apps. Key findings demonstrate emerging AI innovations show promise for enhancing communication, learning, inclusion, and independence for deaf and hard of hearing youth.
View Article and Find Full Text PDFHuman TMC1 and TMC2 are mechanically gated ion channels.
Neuron
December 2024
Institute of Molecular Physiology, Shenzhen Bay Laboratory, Shenzhen, China; Department of Neurobiology, School of Basic Medicine, Capital Medical University, Beijing, China; Institute for Medical Physiology, Chinese Institutes for Medical Research, Beijing, China. Electronic address:
Mammalian transmembrane channel-like proteins 1 and 2 (TMC1 and TMC2) have emerged as very promising candidate mechanotransduction channels in hair cells. However, controversy persists because the heterogeneously expressed TMC1/2 in cultured cells lack evidence of mechanical gating, primarily due to their absence from the plasma membrane. By employing domain swapping with OSCA1.
View Article and Find Full Text PDFStress-Induced Ultrasonic Vocalization in Laboratory Rats and Mice: A Scoping Review.
Brain Sci
October 2024
Division of Otolaryngology-Head & Neck Surgery, Department of Surgery, University of Wisconsin-Madison, Madison, WI 53705, USA.
: Ultrasonic vocalization (USV) can indicate affective states-including psychosocial stress-in mice and rats. However, stress-induced USV changes could be confounded by laboratory experimental variables such as the type of behavioral stress paradigm, the elicitation method, rodent strain, etc. We sought to provide a review of the current literature to delineate how psychosocial stress-altered rodent USVs may be affected by factors of age, sex, strain, species, elicitation paradigm, and stressor.
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