The physical properties of totally implanted systems for long term chemotherapy were tested before and after in vitro and in vivo chemotherapy. The results show that the drugs used (Cisplatin, Vinblastine and Bleomycin) did not alter the mechanical and microscopic properties of the catheter walls. Although the results cannot be extrapolate to others antineoplastic agents, they confirm the usefulness of the systems for long-term chemotherapy.
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