AI Article Synopsis
- Membranoproliferative glomerulonephritis type II (MPGN II), or dense deposit disease, is a serious kidney condition that can lead to kidney failure within a decade and often presents with unique eye abnormalities.
- A case study of a 45-year-old woman with MPGN II showed she developed serious eye issues, including retinal detachment and hemorrhages, six months post-kidney transplant, although the underlying kidney disease did not recur in the transplant.
- The research aims to explore the relationship between eye changes and clinical factors related to kidney transplantation, with findings suggesting ocular manifestations can occur independently from the kidney condition itself.
Article Abstract
Membranoproliferative glomerulonephritis type II (MPGN II), also known as a dense deposit disease, is a chronic progressive kidney disease that often progresses to end-stage renal disease within 10 years. Most patients also have multiple subretinal white spots or drusen-like deposits that are histopathologically identical to the glomerular basement membrane deposits. The purpose is to determine ocular findings in a patient with MPGN II before and after renal transplantation and to correlate them with clinical characteristics related to transplantation and review of literature. We present a case of a 45-year-old female with MPGN II who developed bilateral serous retinal detachment and retinal hemorrhages in the left eye, which appeared 6 months after a renal transplant. Ocular complications in our case, with the exception on the retina, were present at the cornea and iris. Changes to the eyes were independent of the renal disease, because there was no recurrence of MPGN II on the renal graft.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s11255-013-0627-4 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The crescent sign on ocular ultrasound and correlation with elevated intracranial pressure: A prospective cohort study.
Am J Emerg Med
December 2024
Department of Neurology, University of Wisconsin-Madison, Madison, WI, USA. Electronic address:
Objectives: While lumbar puncture (LP) remains gold standard for assessing intracranial pressure (ICP), LP can be difficult to perform and lead to complications. Noninvasive correlations for elevated ICP via ocular ultrasound (OUS) have shown mixed results. The primary objective of this study is to identify the frequency and test characteristics of the crescent sign on OUS for elevated ICP.
View Article and Find Full Text PDFLong-term outcomes of scleral fixated black diaphragm intraocular lens in eyes with combined aphakia and aniridia.
Eur J Ophthalmol
January 2025
Dept of Vitreoretinal Diseases, Sankara Nethralaya, Chennai, India.
Purpose: To evaluate long-term anatomical and functional outcomes in eyes undergoing scleral fixation of aniridic black diaphragm intraocular lens (BDIOL).
Methods: Total 38 eyes that underwent scleral fixation of BDIOL for secondary aniridia following ocular trauma with aphakia with absent posterior capsule or primary congenital aniridia with subluxated lens were retrospectively analyzed. Final visual acuity, early and late complications were examined.
Ten-Year Change in Visual Function and Incidence of Visual Impairment in Highly Myopic Children and Adults.
Invest Ophthalmol Vis Sci
January 2025
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.
Purpose: To investigate the 10-year changes in visual function and incidence of visual impairment (VI) in highly myopic eyes.
Methods: This longitudinal study enrolled highly myopic individuals who were followed up for 10 years. All participants underwent detailed ophthalmic examinations at baseline and follow-up visits.
Maternal immunization impairs lymphoma growth and CNS/ocular metastasis in the offspring.
Front Immunol
January 2025
Alexander Silberman Institute of Life Science, The Hebrew University of Jerusalem, Jerusalem, Israel.
Maternal immunization is an important tool directed against a variety of infectious maladies in the offspring. A complementary, but less explored area is the use of maternal immunization in the prevention and treatment of childhood cancers. This in part stems from the lack of adequate experimental model systems.
View Article and Find Full Text PDFCase report: Improving quality of life through hyaluronic acid-based fillers after orbital cancer treatment.
Front Oncol
December 2024
Department of Pediatrics, Sapienza University, Rome, Italy.
Background: Myoepithelial carcinoma is a very rare yet aggressive tumor in children. Surgical intervention and local radiotherapy often lead to post-therapy complications, affecting both the aesthetic and functional quality of life in survivors. Hyaluronic acid (HA) dermal fillers offer a minimally invasive option to improve the appearance and quality of life for these patients once they are declared tumor-free.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!