A novel composite with an enhanced photocatalytic activity was prepared and applied to study the removal of bezafibrate (BZF), a hypolypemic pharmaceutical, from an aqueous environment. For the enhancement of titanium dioxide photoactivity a fullerene derivative, 2-(ferrocenyl) fulleropyrrolidine (FcC60), was synthesized and applied. Obtained composite was found to show a higher catalytic activity than pristine TiO2. Therefore, high hopes are set in composites that are based on carbonaceous nanomaterials and TiO2 as a new efficient photocatalysts.
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http://dx.doi.org/10.1007/s11356-013-2434-y | DOI Listing |
PLoS One
January 2025
Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.
Associations between variants in the FTO locus and plasma concentrations of appetite related hormones are inconsistent, and might not work in a dose dependent fashion in people with obesity. Moreover, it is relevant to report meal related plasma concentrations of these hormones in persons with obesity given the growing interest in their pharmacological potential in obesity therapy. We find it clinically relevant to examine associations between the SNP rs9939609 genotypes and homeostatic appetite regulation in individuals with BMI ≥35 kg/m2.
View Article and Find Full Text PDFJ Med Chem
January 2025
Sorbonne Université, CNRS Institut Parisien de Chimie Moléculaire, IPCM, F-75005 Paris, France.
Despite recent advances in cancer treatment, there is still a need for novel compounds with antineoplastic activity. Among 11 biphenyl-based organogold(III) -heterocyclic carbene (NHC) (BGC) complexes of general formula [(C^C)Au(NHC-pyr)X], where (C^C) = 4,4'-ditertbutylbiphenyl, X = Cl or phenylacetylide, and (NHC-pyr) is a pyridyl-substituted NHC ligand, the complex bearing a 4-CF-pyridyl substituent and a chloride ligand showed promising antineoplastic activity on the triple negative breast cancer cell line. was able to induce cell apoptosis but had no effect on the cell cycle.
View Article and Find Full Text PDFCerebral ischemia-reperfusion injury (CIRI) constitutes a significant etiology of exacerbated cerebral tissue damage subsequent to intravenous thrombolysis and endovascular mechanical thrombectomy in patients diagnosed with acute ischemic stroke. The treatment of CIRI has been extensively investigated through a multitude of clinical studies. Acupuncture has been demonstrated to be effective in treating CIRI.
View Article and Find Full Text PDFCrit Care Med
December 2024
Department of Psychiatry and Human Behavior, Brown University, Alpert Medical School, Providence, RI.
Objectives: Neurocritically ill patients are at high risk for developing delirium, which can worsen the long-term outcomes of this vulnerable population. However, existing delirium assessment tools do not account for neurologic deficits that often interfere with conventional testing and are therefore unreliable in neurocritically ill patients. We aimed to determine the accuracy and predictive validity of the Fluctuating Mental Status Evaluation (FMSE), a novel delirium screening tool developed specifically for neurocritically ill patients.
View Article and Find Full Text PDFAdv Skin Wound Care
January 2025
In the Department of Surgery, NYU Long Island School of Medicine, Mineola, New York, Sawyer Cimaroli, MD, is Surgical Resident; Danilo Lozada, MS, is Medical Student; and James Daniels, MD, is Surgical Resident. Brian Gillette, PhD, is Research Scientist, Department of Foundation of Medicine, NYU Long Island School of Medicine and Department of Surgery, NYU Langone Hospital Long Island. Scott Gorenstein, MD, is Clinical Assistant Professor, Department of Surgery, NYU Long Island School of Medicine.
Increasing healthcare costs, limited healthcare resources, an aging population, and lifestyle-related diseases make wound management a growing clinical, social, and economic burden. This case series investigated the use of a novel, biocompatible, polymer-based transforming powder dressing (TPD) that transforms in situ to a shape-retentive wound matrix upon hydration for treating wounds of various etiologies.In this institutional review board-approved single-center retrospective case series, the researchers evaluated various acute and chronic wounds treated with TPD over a period of 2 years.
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