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Reactivating Sleeping Intramedullary Nail in a 16-Year-Old Female with Polyostotic Fibrous Dysplasia: A Case Report on Complications and Potential Solutions.
Life (Basel)
November 2024
Pediatric Orthopedics and Traumatology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Background: Fibrous dysplasia (FD) is a rare condition in which normal spongy and cortical bone is replaced by non-neoplastic fibrous tissue, leading to weakened bone matrix and increased risk of pathological fractures and deformities. Treating these deformities poses a significant challenge for surgeons. While various cases of surgical stabilization and limb lengthening using intramedullary nails have been reported, there is limited evidence on the use of Motorized Intramedullary Limb-Lengthening Nails (MILLNs) in FD patients.
View Article and Find Full Text PDFReplantation dilemma: lessons learned from managing a dog bite forearm amputation in a sixteen-year-old girl.
Eur Rev Med Pharmacol Sci
August 2024
Fondazione Policlinico "A. Gemelli" IRCCS, Rome, Italy.
Article Synopsis
- * A case study is presented of a 16-year-old girl who lost her left forearm due to a rottweiler bite, illustrating the difficult decisions in managing severe bite injuries and the need for quick and effective treatment.
- * The conclusion stresses the need for better wound management, psychological support for affected individuals, and increased awareness to prevent dog bites, along with the urgency for clear reporting guidelines and more research in this area.
Management of Nelarabine induced neurotoxicity in a child with T-cell acute lymphoblastic lymphoma.
J Oncol Pharm Pract
April 2024
Department of Paediatric Haematology, Birmingham Children's Hospital, Birmimngham, UK.
Introduction: Nelarabine is now increasingly being used for the treatment of relapsed T-cell acute lymphoblastic leukemia/lymphoma, and about 18% of patients experience ≥ grade 3 toxicity. Despite the increasing use of this drug, there are no guidelines for managing its neurotoxicity. We would like to share our experience with one such case.
View Article and Find Full Text PDFLong-term follow-up in a pediatric patient with Ligneous Conjunctivitis due to PLG gene mutation in topical plasminogen treatment after successful use of ocular prosthesis for aesthetic rehabilitation: a case report.
Ital J Pediatr
August 2023
Rare Diseases and Medical Genetics Unit, Bambino Gesù Children's Hospital, IRCCS, Pediatric Department, Piazza Di Sant'Onofrio, 4, 00165, Rome, Italy.
Background: Ligneous Conjunctivitis (LC) is the most common clinical manifestation of Type I Plasminogen deficiency (T1PD; OMIM# 217090), and it is characterized by the formation of pseudomembranes (due to deposition of fibrin) on the conjunctivae leading to progressive vision loss. In past times, patients with LC were treated with surgery, topical anti-inflammatory, cytostatic agents, and systemic immunosuppressive drugs with limited results (Blood 108:3021-3026, 2006, Ophthalmology 129:955-957, 2022, Surv Ophthalmol 48:369-388, 2003, Blood 131:1301-1310, 2018). The surgery can also trigger the development of membranes, as observed in patients needing ocular prosthesis (Surv Ophthalmol 48:369-388, 2003).
View Article and Find Full Text PDFUnicornuate uterus with noncommunicating functional horn: diagnostic workup and laparoscopic horn amputation.
Fertil Steril
April 2020
Gynaecology and Human Reproduction Physiopathology, Department of Obstetrics and Gynecology, DIMEC, Sant'Orsola Academic Hospital, University of Bologna, Bologna, Italy.
Objective: To describe the diagnosis and the management of hematometra in a patient with unicornuate uterus with noncommunicating functional horn (hemi uterus and rudimentary uterine hemicavity).
Design: Video case report.
Setting: Minimally invasive gynaecology unit.
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