Background And Objective: To measure the subfoveal choroidal thickness in patients with age-related macular degeneration (AMD) over 6 months.

Patients And Methods: A retrospective, observational study of patients with AMD followed up for 6 months at the New England Eye Center. Baseline and 6-month follow-up subfoveal choroidal thickness was measured using spectral-domain OCT and compared.

Results: For the entire cohort, there was statistically significant thinning of the subfoveal choroidal thickness at 6 months compared to baseline that was driven by the cohort of patients with neovascular AMD (181.2 ± 75 μm to 173.4 ± 63 μm; P = .049).

Conclusion: There was a statistically significant decrease in subfoveal choroidal thickness observed in this cohort of patients with AMD over 6 months, but it was driven by the subgroup of patients with neovascular age-related macular degeneration.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069121PMC
http://dx.doi.org/10.3928/23258160-20131220-04DOI Listing

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