AI Article Synopsis
- The absence of dynamic dosimetry tools in permanent prostate brachytherapy leads to preventable issues in patient care for prostate cancer.
- This research aims to create an easily adoptable solution utilizing common ultrasound scanners and mobile C-arms, incorporating a customizable fiducial marker for dynamic dosimetry.
- The system is user-friendly and requires little training, and has been validated through testing on 25 patients, demonstrating its capability to accurately compute doses with minimal manual input, indicating potential for widespread use.
Article Abstract
The lack of dynamic dosimetry tools for permanent prostate brachytherapy causes otherwise avoidable problems in prostate cancer patient care. The goal of this work is to satisfy this need in a readily adoptable manner. Using the ubiquitous ultrasound scanner and mobile non-isocentric C-arm, we show that dynamic dosimetry is now possible with only the addition of an arbitrarily configured marker-based fiducial. Not only is the system easily configured from accessible hardware, but it is also simple and convenient, requiring little training from technicians. Furthermore, the proposed system is built upon robust algorithms of seed segmentation, fiducial detection, seed reconstruction, and image registration. All individual steps of the pipeline have been thoroughly tested, and the system as a whole has been validated on a study of 25 patients. The system has shown excellent results of accurately computing dose, and does so with minimal manual intervention, therefore showing promise for widespread adoption of dynamic dosimetry.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877329 | PMC |
| http://dx.doi.org/10.1117/12.2008097 | DOI Listing |
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