AI Article Synopsis

  • The study presents three cases of childhood-onset systemic lupus erythematosus (SLE) that showed long-term remission without complications from other collagen diseases.
  • These patients maintained no SLE disease activity scores at both 3 and 5 years post-onset, suggesting the possibility of discontinuing maintenance therapy for some.
  • The authors emphasize the importance of individualized monitoring for each patient and the need for standardized remission criteria from clinical trials.

Article Abstract

Abstract Three cases of childhood-onset systemic lupus erythematosus (childhood SLE) with long-term remission are reported. These cases were not complicated with collagen diseases and had no SLE disease activity index scores either 3 or 5 years after onset. We suggest that some patients with childhood SLE may be able to abandon the maintenance therapy, and that careful observation is needed for each individual case. Uniform remission criteria based on clinical trials are needed.

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http://dx.doi.org/10.3109/s10165-003-0238-5DOI Listing

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