Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 1034
Function: getPubMedXML
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3152
Function: GetPubMedArticleOutput_2016
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Objective: to find out the frequency of incidental thyroid carcinoma (ITC) in patients presumably operated for benign thyroid diseases.
Methods: a total of 187 patients undergoing surgery for benign thyroid diseases were included in the study. All the patients underwent fine needle aspiration cytology (FNAC). Only those with benign diseases on FNAC were studied. Patients with undetermined cytology and follicular neoplasm were excluded.
Results: Out of the 187 patients operated histology revealed ITC in 38 (20.3 %) of patients. The mean size of the nodule was 4.28 ± 1.48 cm in benign group and 4.21 ± 1.98 cm in ITC group. Papillary carcinoma was the commonest ITC (97.4 %) and follicular variant (16/38) was found more often than micropapillary variant (3/38). ITC was more common in patients with solitary nodule, 23 of 38 (60.5 %), although it wasn't statistically significant (P value 0.262) 0.33 of 38 (86.8 %) were in euthyroid state (P value 0.029).
Conclusions: the result of this study show, a high frequency of ITC (20.3 %). ITC was more frequent in euthyroid patients (P value 0.029). Incidence of ITC is not significantly different between patients presenting with SNG from those with MNG (P value 0.262). Papillary carcinoma was the commonest ITC (97.4 %) and follicular variant (16/38) was found more often than micropapillary variant (3/38).
Download full-text PDF |
Source |
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585557 | PMC |
http://dx.doi.org/10.1007/s12070-012-0596-4 | DOI Listing |
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