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Circulating irisin levels in patients with MAFLD: an updated systematic review and meta-analysis.
Front Endocrinol (Lausanne)
January 2025
Department of Infectious Diseases, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Article Synopsis
- This systematic review and meta-analysis investigates the connection between circulating irisin levels and metabolic dysfunction-associated fatty liver disease (MAFLD), finding significantly lower irisin levels in MAFLD patients compared to healthy individuals.
- The study included data from 15 case-control studies and highlighted that lower irisin levels were particularly evident in specific populations, such as Asians and individuals over 50, while also showing notable differences based on the severity of the disease and the presence of Type 2 Diabetes (T2DM).
- Overall, the findings reinforce the association between circulating irisin and the progression of MAFLD, despite differences from previous research results.
Magnetic Resonance Imaging Prior Authorizations for Orthopaedic Care Are Negatively Affected by Medicaid Insurance Status.
J Am Acad Orthop Surg
December 2024
From the Department of Orthopaedic Surgery (Harrer, Hedden, Gentile, Gealt, and Brown), Department of Orthopaedic Surgery, Cooper University Health Care, and the Cooper University Health Care (Mikaeili and Bazrafshan), Camden, NJ.
Background: Magnetic resonance imaging (MRI) has revolutionized musculoskeletal care. However, its high costs and high utilization has prompted many insurance payors to require a prior authorization. This process remains burdensome and results in delays to patient care.
View Article and Find Full Text PDFAutomating Racism: Is Use of the Vaginal Birth After Cesarean Calculator Associated with Inequity in Perinatal Service Delivery?
J Racial Ethn Health Disparities
December 2024
Department of Anthropology, History and Social Medicine, University of California, San Francisco, USA.
Objective: The clinical application of race-adjusted algorithms may perpetuate health inequities. We assessed the impact of the vaginal birth after cesarean (VBAC) calculator, which was revised in 2021 to address concerns about equity. The original algorithm factored race and ethnicity and gave lower VBAC probabilities to Black and Hispanic patients.
View Article and Find Full Text PDFParticipation in individual placement support: Ethnoracial differences in the supported employment demonstration.
Psychiatr Rehabil J
December 2024
Westat Inc.
Objective: The Supported Employment Demonstration (SED), a large, multisite randomized controlled trial, provided evidence-based supported employment to help individuals recently denied Social Security disability benefits for reason of mental illness to gain competitive employment and avoid disability. Monthly, client-level measurement of participation in individual placement and support permitted the first detailed exploration of potential ethnoracial disparities in the IPS participation process, from enrollment to end of follow-along job supports, in a vulnerable population with ready access to the intervention.
Method: Monthly participation data in a subsample of enrollees randomized to receive supported employment enabled decomposition of IPS service participation into take-up, effectiveness, and follow-along support phases, yielding times to participation duration milestones, job start, and end of follow-along supports for 614 non-Hispanic White, non-Hispanic Black, and Hispanic SED enrollees.
In the U.S. Court of Appeals for the First Circuit adopted The World Professional Association of Transgender Health Standards of Care (WPATH SOC) as medical consensus on gender affirming care and held that Michelle Kosilek could access gender affirming care but that she did not meet the criteria for gender affirming surgery.
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