A review of 45 consecutive patients who underwent operation for intestinal complications of recurrent gynaecologic cancer was undertaken to elucidate the efficacy of surgical treatment. The primary tumour was ovarian in 26 cases, endometrial in ten and cervical in nine cases. The overall operative mortality was 20%, morbidity 44%, and median survival time and postoperative symptom-free period 5 months and 3 months, respectively. Intestinal resection (n = 12) and bypass procedures (n = 10) carried the lowest mortality risk (8% and 10%). The corresponding figures for enterostomy (n = 15) and exploratory laparotomy (n = 8) were 33% and 25%. Resection gave significantly better survival rate and longer relief of symptoms than the other procedures. Resection and primary anastomosis seems to be the method of choice in low-risk cases. Patients with far advanced cancer or intraabdominal carcinomatosis should be treated surgically only if symptoms cannot be relieved with conservative treatment.
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Colorectal Dis
January 2025
Department of Visceral Surgery, University Digestive Health Care Centre Basel-Clarunis, Basel, Switzerland.
Aim: Ventral mesh rectopexy (VMR) is an established surgical treatment for rectal prolapse and outlet obstruction. In contrast to continental Europe, in the UK and US the use of synthetic mesh has been abandoned in favour of biologic mesh, due to concerns regarding mesh related morbidity. The current study investigated if either material is superior, in terms of clinical recurrence and mesh related complications.
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Department of Biological Sciences, College of Science, King Faisal University, Al-Ahsa, Kingdom of Saudi Arabia.
The outbreak of COVID-19 has opened up new avenues for exploring the importance of vitamin D in immunity, in addition to its role in calcium absorption. Recently, vitamin D supplementation has been found to enhance T regulatory lymphocytes, which are reduced in individuals with COVID-19. Increased risk of pneumonia and increases in inflammatory cytokines have been reported to be major threats associated with vitamin-D deficiency.
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Department of Pathology, Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital, Nagoya, Japan.
A 54-year-old woman was referred to our hospital because of abnormal colonoscopic findings, including a submucosal protuberance at the appendiceal root. A biopsy showed no malignant findings. Computed tomography revealed a 20-mm cystic lesion with thick walls at the appendiceal root, suggestive of an appendiceal mucocele.
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School of Basic Medicine Sciences, Shandong Second Medical University, Weifang, China.
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January 2025
Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.
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