Background: Many studies have examined laser treatment of scars, but cosmetic results have been variable. Although no studies have examined the effect of purpura on scar improvement using the pulsed dye laser (PDL), many clinicians believe inducing purpura results in better and quicker improvement.
Objective: To determine whether PDL treatment of fresh surgical scars with purpura-inducing settings improves clinical appearance more than non-purpura-inducing settings or no treatment.
Methods: Twenty-six subjects with surgical scars enrolled in this prospective study. Scars were divided into three equal segments; treatment was randomized: 595-nm PDL with purpuric (1.5 ms) or nonpurpuric (10 ms) settings or no treatment. Fluences were adjusted to Fitzpatrick skin type. Scars were treated three times, 1 month apart, beginning at suture removal. Outcome measures included Vancouver Scar Scale (VSS) and blind clinical ratings.
Results: The nonpurpuric condition showed significant improvement on the VSS total score, vascularity, and pliability ratings. The purpuric condition demonstrated a trend for improvement on the VSS total. According to blind observer ratings, all conditions improved, without differences between groups.
Conclusion: Nonpurpuric settings on the PDL resulted in significant improvements in the appearance of fresh surgical scars for vascularity, pliability, and VSS total scores, although all scar segments improved over time.
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http://dx.doi.org/10.1111/dsu.12406 | DOI Listing |
Gynecol Oncol Rep
February 2025
Department of Ophthalmology and Visual Science, University of Chicago, Chicago, IL, United States.
Introduction: To report a series of patients who developed ocular surface disease related to tisotumab vedotin-tftv (TV), an antibody-drug conjugate (ADC) approved for the treatment of recurrent or metastatic cervical cancer.
Methods: This was a multicenter retrospective chart review study of patients who developed ocular surface disease related to TV between April 1st, 2022 to August 31st, 2023.
Results: Five patients were identified who developed ocular surface disease while on TV.
Sci Rep
January 2025
Department of Ophthalmology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan.
To assess retinal pigment epithelium (RPE) tears in eyes which underwent pars plana vitrectomy (PPV) for submacular hemorrhage (SMH) secondary to age-related macular degeneration and to investigate the prognostic factors of visual outcomes. This study was a retrospective, observational case series that included 24 eyes of 24 patients who underwent PPV with subretinal tissue plasminogen activator and air for SMH. RPE tears were investigated using spectral-domain or swept-source optical coherence tomography images with raster scan, combined confocal scanning laser ophthalmoscope near-infrared images and color fundus photographs.
View Article and Find Full Text PDFEur J Med Res
January 2025
Women's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Objectives: Choosing the incision for surgery depends on a variety of factors, including the surgeon's preference, patient preference, surgical indications, the patient's systemic issues, previous surgical scars, and other considerations. This trial aimed to evaluate and compare the surgical outcomes of two techniques-Maylard and Cherney incisions-in benign hysterectomy procedures for women.
Materials And Methods: A randomized controlled trial was conducted in Al-Zahra Women's Tertiary Referral University Hospital.
Adv Wound Care (New Rochelle)
January 2025
Department of Dermatology, The Second Affiliated Hospital of Wannan Medic-al College, Wuhu, Anhui, China.
The aim of this study was to compare the long-term effects of fractional carbon dioxide (CO) laser treatment with traditional therapy on surgical scars by analyzing and comparing observational indicators. A randomized controlled trial was conducted on 116 patients who received scar treatment in our hospital, of which 58 patients received fractional CO laser treatment, and 58 patients received injection treatment. The outcome measures comprised the Vancouver Scar Scale (VSS) and the Patient and Observer Scar Assessment Scale (POSAS).
View Article and Find Full Text PDFSurg Technol Int
January 2025
Department of Surgery, Icahn School of Medicine at Mount Sinai, New York, New York.
Thermal or burn injuries cause coagulative necrosis of the epidermis and underlying tissues and the resultant wounds can be long lasting and highly painful. Depending on the depth of a burn, management ranges from local wound care to surgical intervention. When presented with deep-partial thickness and full-thickness burns, autologous skin grafting has been the mainstay of management to prevent scarring and promote healing.
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