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SCoT and ISSR based conservation genetics of Calligonum polygonoides Linn.: An endangered species of Thar desert.
Gene
January 2025
Department of Botany, Mohanlal Sukhadia University, Udaipur 313001, Rajasthan, India. Electronic address:
Calligonum polygonoides, an endangered species of desert due to poor regeneration and overexploitation, which requires immediate conservation attention. Genetic diversity analysis is crucial for effective conservation and management initiatives, for elite genotypes. Therefore, in the present study, SCoT (start codon target) and ISSR (inter simple sequence repeat) markers were used to investigate the genetic variability in 120 individuals of Calligonum polygonoides.
View Article and Find Full Text PDFDevelopmental basis of natural tooth shape variation in cichlid fishes.
Naturwissenschaften
January 2025
Institute of Bioengineering and Biosciences, School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA.
While most dentate non-mammalian vertebrates possess simple conical teeth, some demonstrate complex tooth shapes. Lake Malawi cichlid fishes are an extreme example of this, exhibiting a myriad of tooth shapes driven by an ecologically derived rapid evolution of closely related but distinct species. Tooth shape in mammals is generally considered to be established by signaling centers called primary and secondary enamel knots, which are not believed to be present in non-mammalian vertebrates.
View Article and Find Full Text PDFSSR marker-based genetic diversity and structure analyses of var. from different populations.
PeerJ
January 2025
Guangxi Key Laboratory of Efficacy Study on Chinese Materia Medica, Nanning, Guangxi, China.
Background: var. is a variety in the section of the genus of the family Theaceae which is native to Fangchenggang, Guangxi, China. To date, the genetic diversity and structure of this variety remains to be understood.
View Article and Find Full Text PDFMendelian Randomization Study Reveals Causal Pathways for Hypertrophic Cardiomyopathy, Cardiovascular Proteins, and Atrial Fibrillation.
Br J Hosp Med (Lond)
January 2025
The Cardiology Department of Shanxi Provincial People's Hospital, Shanxi Medical University, Taiyuan, Shanxi, China.
Research evidence has demonstrated a significant association between hypertrophic cardiomyopathy (HCM) and atrial fibrillation (AF), but the causality and pattern of this link remain unexplored. Therefore, this study investigated the causal relationship between HCM and AF using a two-sample and bidirectional Mendelian randomization (MR) approach. Additionally, this assessed the role of cardiovascular proteins (CPs) associated with cardiovascular diseases between HCM and AF by applying a two-step MR analysis.
View Article and Find Full Text PDFImmune Cell Characteristics and Infections Associated with Chronic Obstructive Pulmonary Disease (COPD), Asthma, and Interstitial Lung Disease (ILD): A Mendelian Randomization Studies.
Br J Hosp Med (Lond)
January 2025
Department of Infectious Diseases, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Article Synopsis
- Epidemiological studies reveal that the immune system's role in infections related to COPD, asthma, and ILD is unclear, prompting an investigation into the causal links.
- The study utilized Mendelian randomization methods to analyze genetic data and explored how immune cell signaling affects infection susceptibility in respiratory diseases.
- Results indicated that higher counts of various blood cell types, including white blood cells and their specific subpopulations, are significantly associated with an increased risk of infections related to COPD, asthma, and ILD.
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