Objective: Endoscopic vein harvest (EVH) has been demonstrated to improve early morbidity when compared with conventional open vein harvest (OVH) technique for infrainguinal bypass surgery. However, recent literature suggests conflicting results regarding mid- and long-term patency with EVH. The purpose of this study is to compare graft patency between harvest techniques specifically in patients with critical limb ischemia.

Methods: This retrospective study compared two groups of patients (EVH = 39 and OVH = 49) undergoing lower extremity revascularization from January 2009 to December 2011. Outcome measures included patency rates, postoperative complications, and wound infection. Graft patency was assessed using Kaplan-Meier curves.

Results: Both groups were matched for demographics and indications for bypass (critical limb ischemia). Median follow-up was 22 months. There was a significant reduction in the incidence of wound infection at the vein harvest site in the EVH group (OVH = 20%; EVH = 0%; P < .001), nevertheless, the difference was not significant when only the anastomotic sites were included (OVH = 12.2%; EVH = 15.4%; P = .43). The hospital length of stay was comparable between the two groups (EVH = 8.73 ± 9.69; OVH = 6.35 ± 3.28; P = .26) with no significant difference in the recovery time. Primary graft patency rate was 43.2% in the EVH group and 69.4% in the OVH group (P = .007) at 3 years. The most common reason for loss of primary patency was graft occlusion (61.5%) in the OVH group and vein graft stenosis (54.5%) in the EVH group. The average number of vascular reinterventions per bypass graft was significantly lower in the OVH group compared with the EVH group (OVH = 0.37; EVH = 1.28; P < .001).

Conclusions: Our findings demonstrate inferior primary patency when using the technique of EVH. Additionally, we identified a significantly higher rate of reintervention in the EVH cohort as well as a higher rate of vein graft body stenosis. However, EVH was associated with a decreased rate of wound complications with similar limb salvage and secondary patency rates when compared to OVH. EVH should therefore be selectively utilized in patients at high risk for wound complications.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082991PMC
http://dx.doi.org/10.1016/j.jvs.2013.06.072DOI Listing

Publication Analysis

Top Keywords

evh group
16
evh
15
vein graft
12
critical limb
12
vein harvest
12
graft patency
12
ovh group
12
ovh
10
graft
8
lower extremity
8

Similar Publications

Article Synopsis
  • Previous animal studies indicated concerns about salbutamol's effects on lung injury when exposed to ozone air pollution.
  • A double-blind, randomized, placebo-controlled study involved 18 participants with exercise-induced bronchospasm (EIB) testing the impacts of salbutamol in both ozone and room air during exercise.
  • Results showed that salbutamol significantly improved lung function without increasing airway inflammation, suggesting it is safe for EIB patients to use the medication during high ozone conditions.
View Article and Find Full Text PDF
Article Synopsis
  • This study focuses on the use of noninvasive diagnostic methods to detect esophageal varices (EVs) in patients with compensated cirrhosis, contrasting with the traditional invasive method of upper endoscopy.
  • Conducted on 50 patients at a hospital in Cape Town, the study analyzed various clinical and lab data, showing that 68% of participants had EVs, primarily caused by alcohol, hepatitis B, or autoimmune factors.
  • Key findings emphasize significant differences in factors like liver and spleen stiffness, platelet counts, and dimensions that could enhance the accuracy of noninvasive tools for identifying EVs in patients.
View Article and Find Full Text PDF
Article Synopsis
  • Current guidelines on octreotide therapy duration for esophageal variceal hemorrhage (EVH) are unclear, prompting a randomized clinical trial comparing 24-hour and 72-hour infusions of the drug.
  • The study, which was terminated early due to recruitment issues during COVID-19, found no significant differences in complications or rebleeding rates between the two infusion durations.
  • Results suggested that a 24-hour infusion may be just as effective as a 72-hour infusion, potentially leading to shorter hospital stays and reduced healthcare costs.
View Article and Find Full Text PDF
Article Synopsis
  • Intense physical exercise in adolescents can lead to exercise-induced bronchoconstriction (EIB), which affects 22% of athletes studied, with many being unaware of their condition.
  • The study involved 327 adolescent athletes who underwent various tests, revealing links between EIB, asthma history, and atopy, with many EIB athletes not using inhalation therapy.
  • Effective screening methods like questionnaires and lung function tests were highlighted, emphasizing the need for better detection of EIB, particularly in athletes exposed to air pollution.
View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to see if Opto-Electronic Plethysmography (OEP) can differentiate breathing patterns between athletes with Exercise-Induced Bronchoconstriction (EIB) and those without, analyzing changes during bronchoconstriction and recovery.
  • Researchers examined 47 participants (healthy) and 38 individuals with reported respiratory symptoms, classifying 10 as having EIB based on a specific test, using an extensive motion capture system to gather breathing data.
  • Results showed distinct differences in breathing pattern synchronization between EIB athletes and healthy participants during different conditions, indicating OEP is effective in identifying EIB-related breathing issues.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!