The aim of the present study is the investigation of the potential role of negative relating to others, perceived loneliness, sadness, and anxiety, as mediators of the association between early parental bonding and adult Internet Addiction (IA). The factorial structure of the Internet Addiction Test (IAT) and the prevalence rates of it in a Greek sample will also be investigated. A total of 774 participants were recruited from a Technological Education Institute (mean age=20.2, SD=2.8) and from high school technical schools (mean age=19.9, SD=7.4). The IAT was used to measure the degree of problematic Internet use behaviors; the Parental Bonding Instrument was used to assess one's recalled parenting experiences during the first 16years of life; the shortened Person's Relating to Others Questionnaire was used to assess one's negative (i.e. maladaptive) relating to others (NRO). Both exploratory and confirmatory factor analyses confirmed the three-factor structure of the IAT. Only 1.0% of the sample was severely addicted to the Internet. The mediated effects of only the NRO and sadness were confirmed. Negative relating to others was found to fully mediate the effect of both the father's optimal parenting and affectionless control on IA, whereas sadness was found to fully mediate the effect of the mother's optimal parenting on IA. Overall, the results suggest that parenting style has an indirect impact on IA, through the mediating role of negative relating to others or sadness in later life. Both family-based and individual-based prevention and intervention efforts may reduce the incidence of IA.
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http://dx.doi.org/10.1016/j.addbeh.2013.12.002 | DOI Listing |
Dis Esophagus
January 2025
Department of Digestive and Oncological Surgery, Claude Huriez Hospital, Chu Lille, Lille, France.
Background: Malnutrition is common with esophagogastric cancers and is associated with negative outcomes. We aimed to evaluate if immunonutrition during neoadjuvant treatment improves patient's health-related quality of life (HRQOL) and reduces postoperative morbidity and toxicities during neoadjuvant treatment.
Methods: A multicenter double-blind randomized controlled trial (RCT) was undertaken.
J Infect Dev Ctries
December 2024
The Cancer Hospital Affiliated to Shandong First Medical University (Shandong Cancer Prevention Research Institute, Shandong Cancer Hospital), Jinan 250117, China.
Introduction: In this study, we analyzed the psychological aspects of coronavirus disease 2019 (COVID-19) patients who were discharged from the hospitals in Shanghai, China, and later had positive nucleic acid retest results for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant infection (re-positive COVID-19). The purpose was to gain clarity on the patients' needs and to provide evidence for the medical staff to deliver scientific and targeted health care to the patients.
Methodology: We screened patients who tested positive for SARS-CoV-2 Omicron variant infection by nucleic acid testing after having previously recovered from a COVID-19 infection and being discharged from Shanghai shelter hospitals or COVID-19-designated hospitals from April 3, 2022, to May 10, 2022.
Mol Ther
January 2025
Brown Center for Immunotherapy. Indiana University School of Medicine. 975 W. Walnut St., IB554A, Indianapolis, IN 46202. Electronic address:
Chimeric Antigen Receptor (CAR) T cell therapy has revolutionized cancer treatment and is now being explored for other diseases, such as autoimmune disorders. While the tumor microenvironment (TME) in cancer is often immunosuppressive, in autoimmune diseases, the environment is typically inflammatory. Both environments can negatively impact CAR T cell survival: the former through direct suppression, hypoxia, and nutrient deprivation, and the latter through chronic T cell receptor (TCR) engagement, risking exhaustion.
View Article and Find Full Text PDFLipids Health Dis
January 2025
Department of Urology, Qilu Hospital of Shandong University, 107 Wenhuaxi Road Jinan, Shandong, 250012, People's Republic of China.
Background: An association exists between obesity and reduced testosterone levels in males. The propose of this research is to reveal the correlation between 15 indices linked to obesity and lipid levels with the concentration of serum testosterone, and incidence of testosterone deficiency (TD) among adult American men.
Methods: The study utilized information gathered from the National Health and Nutrition Examination Survey (NHANES) carried out from 2011 to 2016.
Reprod Biol Endocrinol
January 2025
Reproductive Medicine Center, Zhuhai Maternal and Child Health Care Hospital, 543 Ningxi Road, Zhuhai, 519000, China.
Purpose: Prior sperm DNA fragmentation index (DFI) thresholds for diagnosing male infertility and predicting assisted reproduction technology (ART) outcomes fluctuated between 15 and 30%, with no agreed standard. This study aimed to evaluate the impact of the sperm DFI on early embryonic development during ART treatments and establish appropriate DFI cut-off values.
Methods: Retrospectively analyzed 913 couple's ART cycles from 2021 to 2022, encompassing 1,476 IVF and 295 ICSI cycles, following strict criteria.
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