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Giant primary omental cyst: an unusual cause of pseudoascites and hydrocele in a child.
J Surg Case Rep
December 2024
Department of Pediatric Surgery, Hamad Medical Cooperation, Doha 2001, Qatar.
Abdominal lymphangiomas are benign congenital abnormal dilatation and proliferation of lymphatic spaces primarily seen in children. The wide spectrum of symptoms challenges preoperative diagnoses. We present a rare case of a 2-year-old boy presented to pediatrician with massive abdominal distention and left scrotal swelling since the age of 1½ years.
View Article and Find Full Text PDFRefractory Chylous Ascites Leading to Chylothorax Following Extended Right Hepatectomy for Intrahepatic Cholangiocarcinoma.
Cureus
November 2024
Department of Thoracic Surgery, Tenri Hospital, Tenri, JPN.
Chylous ascites, a rare but severe complication of abdominal surgery, often results from lymphatic vessel damage during procedures, such as extended resection and lymphadenectomy. Although conservative management through dietary modifications and medications is the primary approach, refractory cases may lead to severe complications including nutritional deficiencies and even death. Herein, we report a case of refractory chylous ascites that progressed to chylothorax after extended right hepatectomy with lymph node dissection for intrahepatic cholangiocarcinoma.
View Article and Find Full Text PDFHeart Failure Associated with Giant Uterine Leiomyoma: A Case Report.
Medicina (Kaunas)
November 2024
Department of Obstetrics and Gynecology, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec. 2, Chenggong Rd., Neihu District, Taipei City 11490, Taiwan.
Heart failure impairs the heart's pumping ability and triggers catecholamine production as an adaptive mechanism. Uterine leiomyomas are common tumors of the female reproductive tract. Their growth is promoted by dysregulated angiogenesis and gonadal steroid hormones.
View Article and Find Full Text PDFConcentrations of Irinotecan and SN-38 in the Ascites and the Fluid Product of Cell-Free and Concentrated Ascites Reinfusion Therapy 9 Days After Administration of Irinotecan in a Patient with Gastric Cancer: A Case Report.
Onco Targets Ther
November 2024
Department of Oncology and General Medicine, IMSUT Hospital, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Introduction: Cell-free and concentrated ascites reinfusion therapy (CART) is frequently used to relieve the symptoms caused by massive ascites due to peritoneal metastasis of gastric cancer, especially in the later stages of its clinical course. Irinotecan (CPT-11) is recommended for third- or later-line chemotherapy according to gastric cancer treatment guidelines. However, the concentrations of anti-cancer drugs in the ascites and the product of CART are not well known, it is considered that some amounts of anti-cancer drugs contained in the product of CART may be readministered and induce severe adverse reactions.
View Article and Find Full Text PDFIdentification of a Missense Mutation in the Gene from a Chinese Family with Restrictive Cardiomyopathy.
J Multidiscip Healthc
November 2024
Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People's Republic of China.
Article Synopsis
- The study aimed to identify the genetic cause of restrictive cardiomyopathy (RCM) in a family using whole-exome sequencing (WES), highlighting the role of genetic variants in the disease's development.
- A 20-year-old male patient with severe heart failure symptoms was found to have a potentially harmful missense mutation in the filamin-C gene, which was absent in his healthy parents, suggesting it could be a new mutation.
- The discovery of this mutation, previously linked to hypertrophic cardiomyopathy, indicates a genetic overlap between different forms of cardiomyopathy, enhancing the understanding of RCM.
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