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Bolanthus turcicus: a promising antidiabetic with in-vitro antioxidant, enzyme inhibitory and antiadipogenic activities.
J Mol Histol
December 2024
Complementary and Integrative Medicine, Department of Traditional, Ankara Yıldırım Beyazıt University, Ankara, Türkiye, Turkey.
It is crucial to investigate new anti-diabetic agents and therapeutic approaches targeting molecules in potential signaling pathways for the treatment of Type 2 diabetes mellitus (T2DM). The objective of the study was to investigate the total phenolic content, antioxidant capacity, α-glucosidase, and α-amylase inhibitory activities of Bolanthus turcicus (B. turcicus), as well as their cytotoxic, anti-adipogenic, anti-diabetic, apoptotic, and anti-migration potential on adipocytes.
View Article and Find Full Text PDFEarly-Phase Intervention With Traditional Japanese Acupuncture and Moxibustion for Fibromyalgia: A Case Report.
Cureus
November 2024
Department of Traditional Medicine, Toho University, Tokyo, JPN.
Fibromyalgia (FM) is a common chronic pain with no established treatment. Acupuncture is an expected treatment for FM though a diagnosis of FM tends to be delayed, and the advantage is still unclear in early-phase intervention with acupuncture treatment for FM. A 51-year-old woman with panic disorder presented with a four-month history of whole-body pain and was diagnosed with FM.
View Article and Find Full Text PDFSatellite Fingerprinting Methods for GNSS Spoofing Detection.
Sensors (Basel)
December 2024
Institute of Communications and Navigation, German Aerospace Center (DLR), 51147 Köln, Germany.
Spoofing attacks pose a significant security risk for organizations and systems relying on global navigation satellite systems (GNSS) for their operations. While the existing spoofing detection methods have shown some effectiveness, these can be vulnerable to certain attacks, such as secure code estimation and replay (SCER) attacks, among others.This paper analyzes the potential of satellite fingerprinting methods for GNSS spoofing detection and benchmarks their performance using real (in realistic scenarios by using GPS and Galileo signals generated and recorded in the advanced GNSS simulation facility of DLR) GNSS signals and scenarios.
View Article and Find Full Text PDFHIV-1 single transcription start site mutants display complementary replication functions that are restored by reversion.
bioRxiv
December 2024
Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
HIV-1 transcription initiates at two positions, generating RNAs with either 1G or 3G 5' ends. The replication fates of these RNAs di\er, with viral particles encapsidating almost exclusively 1G RNAs and 3G RNAs retained in cells where they are enriched on polysomes and among spliced viral RNAs. Here, we studied replication properties of virus promoter mutants that produced only one RNA 5' isoform or the other: separately, in combination, and during spreading infection.
View Article and Find Full Text PDFA novel energy efficient 4-bit vedic multiplier using modified GDI approach at 32 nm technology.
Heliyon
May 2024
School of Electrical Engineering, University of Johannesburg, Johannesburg 2006, South Africa.
Multipliers are essential components within digital signal processing, arithmetic operations, and various computational tasks, making their design and optimization crucial for improving the efficiency and performance of integrated circuits. Among multiplier architectures, Vedic multipliers stand out due to their inherent efficiency and speed, derived from ancient Indian mathematical principles. This study presents a comprehensive analysis and comparison of 4-bit Vedic multiplier designs utilizing Gate Diffusion Input (GDI), Complementary Metal-Oxide-Semiconductor (CMOS), and Transmission Gate (TG) technologies, utilizing different adder architectures such as Ripple Carry Adder (RCA), and Carry Lookahead Adder (CLA), Carry Skip Adder (CSA).
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