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Advances in multimodal imaging for adrenal gland disorders: integrating CT, MRI, and nuclear medicine.
Jpn J Radiol
January 2025
Department of Diagnostic Radiology, Institute of Science Tokyo, Bunkyo-ku, Tokyo, Japan.
Adrenal diseases pose significant diagnostic challenges due to the wide range of neoplastic and non-neoplastic pathologies. Radiologists have a crucial role in diagnosing and managing these conditions by, leveraging advanced imaging techniques. This review discusses the vital role of computed tomography (CT), magnetic resonance imaging (MRI), and nuclear medicine in adrenal imaging, and focuses on morphological and functional evaluations.
View Article and Find Full Text PDFPrimary intracranial neuroendocrine tumor at the sphenoid ridge with metastasis to the spinal cord: A case report.
Medicine (Baltimore)
December 2024
Department of Neurosurgery, Xiamen Branch of West China Hospital, Sichuan University, Xiamen, P.R. China.
Rationale: Neuroendocrine tumors (NETs) originate from neuroendocrine cells and they are depicted with both nerve cells as well as hormone-producing cells. These tumors were initially discovered in extracranial locations and central nervous system involvement is often a result of metastasis. Herein, we present a very rare case of primary intracranial neuroendocrine tumor (PINET) that masqueraded as meningioma at the sphenoid ridge with metastasis to the spinal cord in a patient without a known history of extracranial NET at the time of diagnosis.
View Article and Find Full Text PDFThe impact of adrenocortical carcinoma hormone secreting status as a predictor of poor survival: a systematic review and meta-analysis.
Langenbecks Arch Surg
October 2024
Third Department of Surgery, National and Kapodistrian University of Athens, Attikon University Hospital, 1 Rimini Str, Athens, 12462, Greece.
Purpose: Adrenocortical carcinoma (ACC) poses a significant challenge in healthcare due to its aggressive nature and rarity. Prior reports suggest a poorer prognosis associated with hormone-secreting neoplasms. This study aims to assess the impact of ACC hormonal status on patients' oncologic survival.
View Article and Find Full Text PDFAdrenocortical carcinoma in a West White Terrier: clinical and diagnostic approach.
Braz J Vet Med
October 2024
Veterinarian, DSc. DMCV, IV, UFRRJ. Seropédica, RJ, Brazil.
Adrenocortical carcinoma (ACC) is a rare condition in dogs. This type of tumor can be functional, hormone-producing, or nonfunctional. Bilateral adrenal tumors are uncommon, whereas unilateral adrenal tumors are more prevalent.
View Article and Find Full Text PDFEssential Role of the RIα Subunit of cAMP-Dependent Protein Kinase in Regulating Cardiac Contractility and Heart Failure Development.
Circulation
December 2024
Université Paris-Saclay, Inserm, Signaling and Cardiovascular Pathophysiology, UMR-S1180 (I.B., M.G.-R., M.D., A.B., A.V., D.M., S.B., J.C., P.L., S.K., M.D., S.G., W.P.d.V., P.M., A.D., J.-J.M., J.-P.B., V.A., J.L., R.F., A.-M.G., G.V.), Orsay, France.
Background: The heart expresses 2 main subtypes of cAMP-dependent protein kinase (PKA; type I and II) that differ in their regulatory subunits, RIα and RIIα. Embryonic lethality of RIα knockout mice limits the current understanding of type I PKA function in the myocardium. The objective of this study was to test the role of RIα in adult heart contractility and pathological remodeling.
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