Guidance on wound debridement has been updated. This article discusses the most commonly used debridement methods recommended in the guidance and gives an overview of new technology. It provides practice points on how to debride a wound successfully.
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Smart biomaterial gels for periodontal therapy: A novel approach.
Biomed Pharmacother
January 2025
Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, 6 Eötvös u., Szeged H-6720, Hungary. Electronic address:
Periodontitis, a chronic inflammatory condition of the oral cavity, is characterized by the progressive destruction of the supporting structures of the teeth. The pathogenic effects of periodontopathogens extend beyond the local periodontal environment, contributing to systemic health complications, thereby underscoring the need for effective therapeutic strategies. Current standard treatments, which involve mechanical debridement coupled with systemic anti-inflammatory and antibiotic therapies, are often associated with limited efficacy, adverse effects, and the emergence of antibiotic resistance.
View Article and Find Full Text PDFUnderstanding the pathophysiology of colonization as a guide for future treatment for chronic leg ulcers.
Burns Trauma
January 2025
Frazer Institute, The University of Queensland, Brisbane, Australia.
Chronic leg wounds represent a major burden of disease worldwide, costing health care systems billions of dollars each year. Aside from the financial implications, they also impose a significant physical and psychosocial burden on the patient, their relatives and/or carers, and the community. Whilst measures such as maintenance of wound hygiene, debridement, dressings and compression are the current standard of care, complete healing is not always achievable and ulcer recurrence is common.
View Article and Find Full Text PDFSurgical consideration and practical difficulty in malignant otitis externa: a systematic review.
Eur Arch Otorhinolaryngol
January 2025
Department of Otology, King Saud University, Riyadh, 11421, Saudi Arabia.
Purpose: This systematic review aims to explore the role of surgery in managing Malignant Otitis Externa (MOE) by analyzing surgical considerations, treatment duration, responses, and patient outcomes.
Methods: A comprehensive search was conducted across PubMed, Science Direct, Google Scholar, and Cochrane Library databases between 2003 and February 2023. Studies meeting inclusion criteria detailed MOE cases, patient medical profiles, surgical procedures undertaken, and treatment outcomes.
Use of reverse sural artery cross leg flap for limb salvage in low resource setting: A case report and literature review.
Int J Surg Case Rep
January 2025
Department of Plastic Surgery, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.
Introduction: Soft tissue defect in the lower limb presents as a difficult reconstructive challenge. Cross-leg flap was routinely used in the past for the salvage of the lower limb but is seldom used nowadays due to advances in microsurgical procedures.
Case Presentation: We present a case of an 18-year-old male who presented with a complex soft tissue defect of 25 × 10 cm on the anterolateral aspect of the right leg following a motor vehicle accident.
An Unusual Case of Giant Polymicrobial Shoulder Abscess Developing Two Decades After an Insect Bite: The Role of Chronic Intermittent Swelling as a Predisposing Factor.
Cureus
December 2024
Department of Orthopaedics and Traumatology, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, TUR.
Shoulder abscesses, commonly resulting from bacterial infections, can occasionally present with atypical etiologies and delayed onset. We report a rare case of a massive polymicrobial shoulder abscess developing two decades after an insect bite, emphasizing its clinical presentation, diagnostic approach, and surgical management. A 65-year-old female presented with severe, progressively worsening right shoulder pain, a 20 cm swelling, and purulent discharge persisting for 15 days.
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