Oral lesions indicative of biopsy represent unique presentation either in the form of proliferations/ulcerations of the squamous lining epithelium. These lesions have similar appearance clinically and histopathologically hence are excised for microscopic evaluation to rule out early or hidden malignancy. Verrucous mucosal lesions clinically present a diagnostic dilemma, which makes histopathological examination a significant one in the differentiation of the lesion to ascertain the nature. This short communication aims to discuss the different histological characterization of oral verrucous mucosal lesions.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.4103/0970-9290.123421 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
DNA methylation analysis from oral brushing reveals a field cancerization effect in proliferative verrucous leukoplakia.
Pathologica
December 2024
Functional and Molecular Neuroimaging Unit, Bellaria Hospital, Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
Objectives: The aim of the present study was to analyze the methylation status in patients who presented with an Oral Squamous Cell Carcinoma (OSCC) concomitantly with multifocal Proliferative Verrucous Leukoplakia (PVL)(PVL-OSCC).
Methods: Nine patients with OSCC and concomitant PVL lesions were selected. Two brushing samples were collected simultaneously from OSCC and PVL lesions in contralateral mucosa from each patient.
Demographic and clinicopathological comparison among oral lichen planus, lichenoid lesions and proliferative verrucous leukoplakia: a retrospective study.
BMC Oral Health
December 2024
Dental Sciences Graduate Program. Federal University of Espirito Santo (UFES), Avenida Maruípe 1468, Maruípe, Vitória, 29040-090, ES, Brazil.
Article Synopsis
- The study focused on comparing oral lichen planus and related lesions due to their risk of becoming cancerous and the need to differentiate them from similar conditions.
- Researchers conducted a survey among patients to collect sociodemographic and clinical data, analyzing this information using statistical tests.
- The findings revealed distinct characteristics for each type of lesion, with lichen planus showing reticular patterns and the buccal mucosa being the most affected area, while proliferative verrucous leukoplakia was linked with significant epithelial dysplasia.
Case report: Non-invasive cyto-salivary sampling and biomarker detection via ELISA versus histopathology for diagnosing oral potentially malignant disorders - Insights from a case-control study.
Front Immunol
December 2024
Department of Experimental Medicine (DIMES), University of Genoa, Genoa, Italy.
Oral leukoplakia is classified among oral potentially malignant disorders (OPMDs) by the World Health Organization (WHO). The visual oral examination (VOE) is the most used method for identifying lesions in their early stages. Given that the diagnosis of oral cancer is often late, there is an urgent need for early detection and examination of oral lesions.
View Article and Find Full Text PDFOral Verruciform Xanthoma of the Lower Lip: A Rare Entity.
Cureus
November 2024
Oral Pathology and Microbiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Oral verruciform xanthoma (OVX) is a rare entity, and only a handful of cases have been reported in the literature to date. This innocent-looking lesion can mimic any benign epithelial or connective tissue origin neoplasm. It can present with variations in surface color and texture.
View Article and Find Full Text PDFPrognostic implications across histological subtypes of head and neck squamous cell carcinoma: An update.
J Stomatol Oral Maxillofac Surg
November 2024
Department of Pathology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil. Electronic address:
Article Synopsis
- * This review examines existing research on the prognostic implications of HNSCC’s histopathologic subtypes, noting a lack of studies focusing specifically on treatment outcomes for each subtype.
- * The review highlights that some subtypes, like verrucous and cuniculatum, have better prognoses compared to others like basaloid and spindle cell, and it emphasizes the need for more molecular research to develop targeted therapies and improve prognostic assessments.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!