Formation and Direct Repair of UV-induced Dimeric DNA Pyrimidine Lesions.

Photochem Photobiol

Center for Integrated Protein Sciences at the Department of Chemistry, Ludwig-Maximilians Universität München, Munich, Germany.

Published: January 2014

Direct repair of UV-induced DNA lesions represents an elegant method for many organisms to deal with these highly mutagenic and cytotoxic compounds. Although the participating proteins are structurally well investigated, the exact repair mechanism of the photolyase enzymes remains a vivid subject of current research. In this review, we summarize and highlight the recent contributions to this exciting field.

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Source
http://dx.doi.org/10.1111/php.12197DOI Listing

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