Does the new formulation of OxyContin® deter misuse? A qualitative analysis.

Subst Use Misuse

1Department of Behavioral Science, University of Kentucky, Lexington, Kentucky, USA.

Published: May 2014

AI Article Synopsis

  • The study explores how drug use patterns have changed in rural Appalachia after a new version of OxyContin® was released to limit misuse.
  • Participants included 25 individuals from a larger group of 192 rural drug users, who were interviewed in 2011 about their experiences.
  • The main outcome revealed that most participants shifted from using the original OxyContin to immediate-release oxycodone, and the study discusses the implications and limitations of these findings.

Article Abstract

The purpose of this qualitative study is to understand changing illicit drug use patterns in rural Appalachia since a new formulation of OxyContin® was released with the goal of deterring diversion and misuse. Participants (n = 25) from a longitudinal study of rural drug users (N = 192) were approached to participate in semistructured qualitative interviews between April and June 2011. The primary finding is that the majority of participants switched from using the original formulation OxyContin to immediate-release oxycodone. We discuss the implications and limitations of these findings.

Download full-text PDF

Source
http://dx.doi.org/10.3109/10826084.2013.866963DOI Listing

Publication Analysis

Top Keywords

formulation oxycontin®
8
oxycontin® deter
4
deter misuse?
4
misuse? qualitative
4
qualitative analysis
4
analysis purpose
4
purpose qualitative
4
qualitative study
4
study understand
4
understand changing
4

Similar Publications

Objective: The study aims to develop continuous trajectory profiles along curves with minimal error. It also focuses on formulating a percentage trajectory transection rate model as a function of geometric parameters (e.g.

View Article and Find Full Text PDF

Treating Opioid Use Disorder and Opioid Withdrawal in the Context of Fentanyl.

Annu Rev Clin Psychol

January 2025

Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; email:

The opioid crisis, driven by illicitly manufactured fentanyl, presents significant challenges in treating opioid use disorder (OUD) and opioid withdrawal syndrome. Fentanyl is uniquely lethal due to its rapid onset and respiratory depressant effects, driving the surge in overdose deaths. This review examines the limitations of traditional diagnostic criteria like those of the , Fifth Edition, Text Revision (DSM-5-TR) and explores the potential of dimensional models such as the Hierarchical Taxonomy of Psychopathology (HiTOP) for a more nuanced understanding of OUD.

View Article and Find Full Text PDF

Control Principles of Neural Dynamics Revealed by the Neurobiology of Timing.

Annu Rev Neurosci

January 2025

1Department of Brain and Cognitive Sciences, McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; email:

Cognition unfolds dynamically over flexible timescales. A major goal of the field is to understand the computational and neurobiological principles that enable this flexibility. Here, we argue that the neurobiology of timing provides a platform for tackling these questions.

View Article and Find Full Text PDF

Strategies and Prospects for Engineering a Stable Zn Metal Battery: Cathode, Anode, and Electrolyte Perspectives.

Acc Chem Res

January 2025

Department of Chemistry, Shanghai Key Laboratory of Catalysis and Innovative Materials, Center of Chemistry for Energy Materials Shanghai, Fudan University, Shanghai 200433, PR China.

ConspectusZinc metal batteries (ZMBs) appear to be promising candidates to replace lithium-ion batteries owing to their higher safety and lower cost. Moreover, natural reserves of Zn are abundant, being approximately 300 times greater than those of Li. However, there are some typical issues impeding the wide application of ZMBs.

View Article and Find Full Text PDF

Chemotherapy-induced peripheral neuropathy (CIPN) is a serious side effect of anticancer agents with limited effective preventive or therapeutic interventions. Although fenofibrate, a peroxisome proliferator-activated receptor-alpha (PPARα) agonist, has demonstrated neuroprotective and analgesic properties, its clinical utility is hindered by low receptor affinity, poor subtype selectivity, and suboptimal bioavailability. A190, a highly selective and potent nonfibrate PPARα agonist, offers a promising alternative but is limited by poor aqueous solubility, resulting in reduced oral bioavailability and therapeutic efficacy.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!