Anaplastic Solitary plasmacytoma of mandible, masquerading as sarcoma.

Pak J Med Sci

Bijan Khademi, MD, Department of Otolaryngology, Shiraz University of Medical Science, Shiraz, Iran.

Published: May 2013

Plasma cell neoplasm is characterized by a monoclonal neoplastic proliferation of plasma cells and solitary plasmocytoma of bone (SPB) is a localized form. It usually occurs in vertebrae and secondarily in long bones. Its presence in mandible is extremely rare event. A 48-year-old man consulted to our clinic with a chief complaint of pain in his mandible. Radiography revealed a destructive lesion in body and ramus. The initial pathologic evaluation revealed a high grade pleomorphic neoplasm. The diagnosis was confirmed by immunohistochemical markers. Overall, plasmacytoma with anaplastic features can be confused with high grade sarcoma clinically and histologically.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809276PMC
http://dx.doi.org/10.12669/pjms.293.3406DOI Listing

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