Utilizing combinatorial chemistry and rational design: peptidic tweezers with nanomolar affinity to DNA can be transformed into efficient vectors for gene delivery by addition of a lipophilic tail.

Angew Chem Int Ed Engl

Institute for Organic Chemistry, University of Duisburg-Essen, 45117 Essen (Germany); Current address: Stanford University, Department of Chemistry, Stauffer I, Stanford, CA 94305 (USA).

Published: December 2013

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http://dx.doi.org/10.1002/anie.201306929	DOI Listing

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