Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853919 | PMC |
| http://dx.doi.org/10.4103/2229-5178.120663 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A challenging case of Kyrle's disease successfully treated with apremilast.
Indian J Dermatol Venereol Leprol
November 2024
Department of Dermatology, Venereology and Leprosy, ESIC Medical College & Hospital, Faridabad, India.
An Unusual Case of Kyrle Disease.
Cureus
August 2024
Dermatology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pune, IND.
Article Synopsis
- Kyrle disease is an acquired perforating disorder linked to conditions like type 2 diabetes and chronic kidney disease, characterized by skin lesions that show transepidermal elimination of dermal contents upon histopathological examination.
- In the reported case, the patient exhibited only hyperuricemia as an abnormal lab finding, with no typical associated conditions present, making the cause of the disease unclear.
- Treatment focused on addressing the underlying issues; however, the patient saw improvement with medications like acitretin, dapsone, and topical corticosteroids, highlighting the need for more research on factors like hyperuricemia in cases lacking classic associations.
A Case of Noonan Syndrome and Kyrle's Disease: Coincidence or Causality?
Acta Dermatovenerol Croat
March 2024
Marco Brusasco, MD, University of Parma, Via Gramsci 14, Parma, Italy;
Article Synopsis
- A 39-year-old woman with Noonan Syndrome and a RAF1 mutation presented with itchy lesions on her limbs that developed two months prior, characterized by multiple dome-shaped papules.
- Blood tests showed no abnormalities, but a skin biopsy revealed features consistent with Kyrle's disease, a type of perforating dermatosis.
- The patient was treated with narrowband UVB phototherapy, resulting in complete resolution of symptoms despite leaving residual atrophic scars.
Recalcitrant Reactive Perforating Collagenosis Successfully Treated with Dupilumab: A Case Report.
Clin Cosmet Investig Dermatol
June 2024
Department of Dermatology, Peking University People's Hospital, Beijing, People's Republic of China.
Reactive perforating collagenosis (RPC) is the most common form of the perforating dermatoses, which include RPC, elastosis perforans serpiginosa (EPS), perforating folliculitis (PF), and Kyrle disease (KD). In RPC, altered collagen of the dermis is extruded through the epidermis, which can be misdiagnosed as other skin diseases, such as vasculitis or prurigo nodularis. RPC is associated with a number of conditions, including diabetes mellitus, hepatitis, and renal failure, and thus the management of the coexisting diseases is important.
View Article and Find Full Text PDFA Case of Noonan Syndrome and Kyrle Disease: Casualty or Causality?
Acta Dermatovenerol Croat
December 2023
Marco Brusasco, MD, Dermatology Section Department of Medicine and Surgery, University of Parma, Via Gramsci, 14, 43126 Parma, Italy;
Article Synopsis
- A 39-year-old woman with Noonan Syndrome and RAF1 mutation presented with itchy skin lesions on her limbs, which were diagnosed as Kyrle disease (KD) after a detailed examination.
- KD is characterized by dome-shaped papules with a central keratotic plug and is often linked to systemic conditions such as chronic renal failure and diabetes, although this patient did not have these issues.
- Treatment involved narrowband UVB phototherapy, leading to complete resolution of symptoms, which highlights the importance of managing underlying health conditions in skin diseases like KD.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!