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Management of Extramammary Paget's Disease: A Case Report and Review of the Literature. | LitMetric

Management of Extramammary Paget's Disease: A Case Report and Review of the Literature.

Case Rep Dermatol Med

Department of Surgery, School of Medicine at Amarillo, Texas Tech University Health Sciences Center, 1400 S Coulter Street, Amarillo, TX 79106, USA ; Gastrointestinal and Hepato-Pancreato-Biliary Surgery, Division of Surgical Oncology, Texas Tech University Health Sciences Center, 1400 S Coulter Street, Amarillo, TX 79106, USA.

Published: December 2013

AI Article Synopsis

  • - Extramammary Paget's Disease (EMPD) primarily affects areas like the vulva, scrotum, and axilla, but it's rare overall and can be linked to cancers in other organs.
  • - The report discusses a specific case where treatment with imiquimod 5% cream was unsuccessful for scrotal EMPD, highlighting the challenges in managing this condition.
  • - It stresses the need for more research to improve treatment options, given the mixed success rates of current therapies.

Article Abstract

Extramammary Paget's Disease (EMPD) is a rare condition of the skin that often involves the vulva, perianal region, scrotum, penis, and axilla. Although prognosis is generally favorable, it can be associated with neoplasms of the bladder, urethra, prostate, and rectum. This report presents a case of scrotal EMPD that failed treatment with imiquimod 5% cream and discusses benefits and complications of available treatment options. The variation of treatment success emphasizes the importance of further research.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848195PMC
http://dx.doi.org/10.1155/2013/436390DOI Listing

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