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Diffuse neurofibroma--an uncommon cause of alopecia. | LitMetric

Diffuse neurofibroma--an uncommon cause of alopecia.

An Bras Dermatol

Instituto Português de Oncologia Francisco Gentil, Department of Pathological Anatomy, Lisbon, Portugal.

Published: May 2014

AI Article Synopsis

Article Abstract

Although infrequent, alopecia can be caused by benign cutaneous tumours. Neurofibromas are common benign tumors that originate in the peripheral nerve sheath. Diffuse neurofibroma is a rare variant of neurofibroma that is thought to occur mainly in the head and neck of children and young adults. Histology generally shows an infiltrative tumor, composed of spindle cells in the dermis and subcutaneous tissue. Despite being rare, malignant transformation has been reported. The association between diffuse neurofibromas and neurofibromatosis type 1 still remains to be determined since some authors question the low incidence usually described. We report the case of a 42-year-old man who had a diffuse neurofibroma on the scalp presenting as alopecic plaques.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876007PMC
http://dx.doi.org/10.1590/abd1806-4841.20132170DOI Listing

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