Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/JCP.0b013e3182a60862 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Nicotinamide Prevents The Plasticity Impairments And The Cognitive Dysfunction Caused By Bone Fracture In Older Mice.
J Gerontol A Biol Sci Med Sci
January 2025
Centro de Investigación Clínica Avanzada (CICA), Hospital Clínico Universidad de Chile.
Postoperative delirium (POD), an acute cognitive dysfunction linked to morbidity and mortality, is characterized by memory impairments and disturbances in consciousness, particularly in patients aged 65 and older. Neuroinflammation and NAD+ imbalance are key mechanisms behind POD, leading to synaptic and cognitive deterioration. However, how surgery contributes to POD and neuroinflammation remains unclear, and effective treatments are lacking.
View Article and Find Full Text PDFTiming of risk factors, prodromal features, and comorbidities of dementia from a large health claims case-control study.
Alzheimers Res Ther
January 2025
Department of Epidemiology and Healthcare Atlas, Central Research Institute of Ambulatory Health Care in Germany, Berlin, Germany.
Background: Many risk factors for dementia have been identified, but the timing of risk is less well understood. Here, we analyzed risk factors in a case-control study covering 10 years before an incident dementia diagnosis.
Methods: We designed a case-control study using insurance claims of outpatient consultations of patients with German statutory health insurance between January 1, 2012, and December 31, 2022.
Development of a LASSO machine learning algorithm-based model for postoperative delirium prediction in hepatectomy patients.
BMC Surg
January 2025
Department of Anaesthesiology, Central People's Hospital of Zhanjiang, Zhanjiang, Guangdong, China.
Objective: The objective of this study was to develop and validate a clinically applicable nomogram for predicting the risk of delirium following hepatectomy.
Methods: We applied the LASSO regression model to identify the independent risk factors associated with POD. Subsequently, we utilized R software to develop and validate a nomogram model capable of accurately predicting the incidence of POD.
Association between delirium severity and prognosis following Transcatheter aortic valve implantation.
J Cardiol
January 2025
Department of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan.
Background: Delirium is associated with patient prognosis after transcatheter aortic valve implantation (TAVI). However, the prognostic impact of subsyndromal delirium, described as an intermediate stage between delirium and normal cognition, is uncertain. The present study aimed to investigate the prognostic impact of delirium severity in patients undergoing TAVI.
View Article and Find Full Text PDFCharacterizing Difficulties and Management of Sleep Disturbances in a Tertiary Palliative Care Unit-A Retrospective Review.
J Palliat Care
January 2025
Departments of Internal Medicine and Family Medicine, Section of Palliative Care Medicine, University of Manitoba, Winnipeg, Canada.
Difficulty sleeping is common in palliative care, however often unrecognized by palliative care physicians. This retrospective review aims to gain a better understanding of the causes and treatment of sleeping disturbances in a tertiary palliative care unit. This study included 200 palliative care inpatients admitted between January 1, 2015, and August 31, 2020.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!