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Para-aminopropiophenone toxicity in domestic dogs: a description of non-target toxicosis in Victoria, Australia: 13 dogs (2016-2023).
Aust Vet J
January 2025
Melbourne Veterinary School, University of Melbourne, Werribee, Victoria, Australia.
Background: PAPP is widely used in Australia as a potent vertebrate bait, with potential for off-target ingestion and poisoning in domestic dogs. Whilst toxicosis and resulting methaemoglobinaemia is anecdotally known to occur, this is the first description in the literature. This study reports thirteen clinical cases of suspected Para-aminopropiophenone (PAPP) toxicity in dogs, with the aim of describing clinical presentation and current management of toxicosis in this species.
View Article and Find Full Text PDFAcute hemolytic crisis complicated with ischemic cardiac injury and methemoglobinaemia following ingestion of naphthalene: a case report.
J Med Case Rep
December 2024
Faculty of Healthcare Sciences, Eastern University of Sri Lanka, Chenkaladi, Sri Lanka.
Background: Naphthalene is an aromatic hydrocarbon that potentially produces methemoglobinaemia but rarely causes hemolysis, especially in children with underlying glucose-6-phosphate dehydrogenase deficiency. Although ingestion of a single moth ball by an older child may not be life threatening, it can be fatal if ingested by a toddler.
Case Presentation: A 2-year-old Singhalese boy developed acute severe hemolysis and methemoglobinaemia following ingestion of a mothball.
Refractory methemoglobinemia after ingestion of -dimethyl--toluidine.
Clin Toxicol (Phila)
December 2024
Department of Emergency Medicine, Chang Gung Memorial Hospital, Linkou, Taiwan.
A 10-year retrospective review of exposures to volatile nitrites reported to the Victorian Poisons Information Centre.
Clin Toxicol (Phila)
November 2024
Pharmacy Department, Austin Health, Heidelberg, Australia.
Article Synopsis
- Volatile nitrites, like amyl nitrite, are recreationally used for enhanced sexual experiences but can lead to serious health issues, prompting a study from the Victorian Poisons Information Centre covering a decade.
- Over ten years, there was a significant rise in reported cases, with 132 calls about 122 exposures, often linked to ingestion and inhalation; common symptoms included dizziness, irritation, and nausea, while more serious effects occurred in a minority of cases.
- The study highlights the increasing use of volatile nitrites in Australia, underscoring the need for improved community education and harm reduction strategies among users and healthcare providers.
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