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Histologic and immunohistochemical studies (use of antibodies for viruses of herpes simplex type 1 and 2, desmin, vimentin, SMA as well as polymerase chain reaction to DNA of viruses of herpes simplex) were made on the material of the valves taken from 1326 patients with valvular heart disease, the ascending aorta of 30 patients with aneurysm, valves of 35 deceased patients without cardiovascular pathology. As a result, expression of viruses of herpes simplex type 1 and/or 2 was found in all cases with mesenchymal dysplasia and cystic medianecrosis in endotheliocytes, fibroblasts, smooth muscle cells of valves and aorta. This indicates the role of these viruses in the pathogenesis of these diseases and their common etiology.
View Article and Find Full Text PDFIn long-term period after resection of aorta coarctation, 9-14% patients developed aortic aneurysms, one third of them localized in the ascending aorta. From 146 patients operated on for aneurysm of the ascending aorta, 3 had aortic coarctation. In 2 patients aneurysms of the ascending aorta formed late after resection of the coarctation, the third patient was hospitalized with clinical picture of cardiac insufficiency at terminal stage due to coarctation of the aorta and a giant aneurysm of the ascending aorta with significant aortic insufficiency.
View Article and Find Full Text PDF[Influence of anatomo-pathological involvement of the aorta on results of Bentall's operation].
Arch Mal Coeur Vaiss
January 1995
Service de chirurgie cardiovasculaire et cardiaque pédiatrique, centre chirurgical Marie-Lannelongue et université Paris.
The results of 51 patients undergoing the Bentall procedure for aneurysmal pathology of the ascending aorta during the last 10 years are analysed with respect to the nature of the pathology of the lesions of the arterial wall. The study population comprised 39 men and 12 women with a mean age of 47 +/- 17 years (range 2-76 years). They were divided into two groups, Group I (n = 38) with degenerative cystic medianecrosis, Group II (n = 13) with atheromatous lesions.
View Article and Find Full Text PDF[Chronic dissecting aortic aneurysm and Turner's syndrome. Apropos of a case].
Arch Mal Coeur Vaiss
July 1992
Service de cardiologie, hôpital Meyer, Florence, Italie.
Turner's syndrome is a genetic abnormality which is associated with cardiovascular anomaly in 20% of cases. Coarctation of the aorta and bicuspid aortic valve are the commonest malformations. Aortic dissection is the most serious complication affecting these patients.
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