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A red or blue mucous membrane disorder of the oral cavity can arise in response to a local cause of irritation, as a cause of an inflammation reaction to an infection, an auto-immune reaction to a local factor, and as an expression of an underlying systemic disorder. Moreover, it can be an expression of a premalignant or malignant mucous membrane disorder. Knowledge about and recognition of the different red and blue mucous membrane disorders can hasten the diagnosis and possible treatment. In the case of a premalignant (erythroplakia) or a malignant mucous membrane disorder (squamous cell carcinoma), the prognosis is better with early diagnosis and treatment than at a later stage of the disease.
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http://dx.doi.org/10.5177/ntvt.2013.11.13212 | DOI Listing |
Cell Death Dis
March 2025
National Clinical Research Center for Digestive Diseases, Department of Gastroenterology, Changhai Hospital, Naval Medical University, Shanghai, China.
Mitochondrial dysfunction contributes to the pathogenesis of ulcerative colitis (UC). As a mitochondrial isozyme of creatine kinases, which control energy metabolism, CKMT1 is thought to be a critical molecule in biological processes. However, the specific role of CKMT1 in intestinal inflammation remains largely unknown.
View Article and Find Full Text PDFWorld J Surg Oncol
March 2025
Division of Otolaryngology and Head and Neck Surgery, IEO, European Institute of Oncology IRCCS, Via Ripamonti 435, Milan, 20141, Italy.
Background: Oral squamous cell carcinoma (OSCC) is the sixth most common cancer globally. Patient survival varies depending on tumour stage and oral cavity subsites. Buccal mucosa neoplasia is rare and burdened by worse prognosis than other oral subsites, showing a high rate of loco-regional relapses within six months after treatment.
View Article and Find Full Text PDFSci Rep
March 2025
Department of Biomolecular Health Sciences, Division Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
Probiotic bacteria including Bifidobacterial species have the capacity to improve intestinal health, but the underlying molecular mechanisms are often not understood. Bifidobacteria are considered keystone species but have a relatively low abundance in the adult intestinal tract. Bifidobacterium colonization depends on degradation of host-derived carbohydrates, including human milk oligosaccharides and mucin-associated oligosaccharides.
View Article and Find Full Text PDFPestic Biochem Physiol
April 2025
School of Plant Protection, Anhui Agricultural University, Hefei, Anhui Province 230036, China; Key Laboratory of Agri-products Quality and Biosafety (Anhui Agricultural University), Ministry of Education, Hefei, Anhui Province 230036, China. Electronic address:
Multiple pesticide residues in the diet can be ingested through the intestine; however, the interactions affecting intestinal health remain unclear. Histopathological analysis of mouse intestines revealed synergistic damage in those exposed to a binary mixture of abamectin, fluazinam, and spirodiclofen. The combined exposure to fluazinam and spirodiclofen resulted in a 73.
View Article and Find Full Text PDFElife
March 2025
Department of Cell Biology, Duke University, Durham, Durham, United States.
Dietary protein absorption in neonatal mammals and fishes relies on the function of a specialized and conserved population of highly absorptive lysosome-rich enterocytes (LREs). The gut microbiome has been shown to enhance absorption of nutrients, such as lipids, by intestinal epithelial cells. However, whether protein absorption is also affected by the gut microbiome is poorly understood.
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