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An Overview of Zika Virus and Zika Virus Induced Neuropathies.
Int J Mol Sci
December 2024
Department of Entomology, Pennsylvania State University, University Park, PA 16802, USA.
Flaviviruses pose a major public health concern across the globe. Among them, Zika virus (ZIKV) is an emerging and reemerging arthropod-borne flavivirus that has become a major international public health problem following multiple large outbreaks over the past two decades. The majority of infections caused by ZIKV exhibit mild symptoms.
View Article and Find Full Text PDFHistologically confirmed pediatric extracardiac rhabdomyoma: case series.
Discov Oncol
January 2025
Department of Pathology, St. Paul Millennium Medical College and ONCO Pathology Diagnostic Center, Addis Ababa, Ethiopia.
Rhabdomyoma is a rare benign tumor of striated muscle, which can be either cardiac or extracardiac. Extracardiac rhabdomyomas can occur throughout the body, though the fetal and adult subtypes are most commonly found in the head and neck region.We present three pediatric cases of extracardiac rhabdomyoma, fetal subtype, detailing their clinical presentations, computed tomography imaging, and tissue biopsy findings.
View Article and Find Full Text PDFSurgical parathyroidectomy in pregnancy for severe secondary hyperparathyroidism associated with end-stage kidney disease.
BMJ Case Rep
January 2025
Maternity Services, The Royal Women's Hospital, Parkville, Victoria, Australia.
Secondary hyperparathyroidism (SHPT) is common in patients with end-stage kidney disease (ESKD) on kidney replacement therapy, which leads to abnormalities of bone and mineral metabolism. Patients conceiving on kidney replacement therapy add a further layer of complexity to the management of their SHPT. Existing literature in cases of primary hyperparathyroidism (PHPT) has linked untreated hyperparathyroidism to increased maternal and fetal morbidity, including hypertensive disorders of pregnancy, fetal growth restriction and neonatal hypocalcaemia.
View Article and Find Full Text PDFMode of birth in nulliparous term singleton pregnancies in vertex presentation before and after implementation of an evidence-based intervention: quality-improvement study.
J Matern Fetal Neonatal Med
December 2025
2nd Department of Gynecology and Obstetrics, University Hospital Bratislava and Comenius University, Bratislava, Slovakia.
Purpose: The main objective of this study was to assess the impact of a composite quality improvement intervention on mode of birth in nullipara term singleton vertex (NTSVs).
Material And Methods: This was an ambidirectional study following the implementation of the intervention to reduce cesarean section rate in NSTV by comparing two birth cohorts, pre-composite quality improvement intervention cohort (January 2013-December 2015) and post-composite quality improvement intervention cohort (January 2018-December 2020).
Results: In the studied periods, there was a total of 7713 NTSV births.
Dysregulated LINC01133 expression in laryngeal carcinoma: Prognostic implications and predicted ceRNA interactome.
Mol Biol Res Commun
January 2025
Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Article Synopsis
- LINC01133 is a long non-coding RNA (lncRNA) that plays crucial roles in cancer, with this study focusing on its expression and impact in laryngeal squamous cell carcinoma (LSCC).
- Integrative analysis of genetic data revealed LINC01133 is significantly downregulated in LSCC compared to normal tissues, and lower levels are linked to advanced tumor stages and lymph node metastasis.
- The study suggests that LINC01133 may act as a tumor suppressor by disrupting microRNA interactions, indicating its potential diagnostic and therapeutic importance in LSCC.
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