AI Article Synopsis
- Calcifications in abdominal cancers can have important diagnostic and prognostic implications, but understanding their significance is complex.
- Certain cancers like colorectal and ovarian are known to calcify, but calcifications can arise from various types of tumors including epithelial and mesenchymal neoplasms.
- Recognizing the different presentations and causes of calcifications can help radiologists better evaluate the disease and inform treatment decisions.
Article Abstract
For the radiologist, calcifications in an abdominal malignancy raise questions of both diagnostic and prognostic significance. Although certain cancers are well known to calcify, such as colorectal and ovarian, malignant abdominal calcifications actually arise from a wide variety of epithelial, mesenchymal, lymphoid, or germ cell neoplasms. The pathophysiology of calcification in abdominal malignancies is heterogeneous and incompletely understood. Calcifications may present primarily, in untreated tumors, or develop during treatment; the latter can occur in variable clinical settings. A basic understanding of the varied pathogenic etiology can assist the radiologist in assessing disease status. By presenting an assortment of calcified abdominal malignancies on computed tomography in varied clinical settings, we aim not only to inform the differential diagnosis, but also to clarify the prognosis of calcifications in abdominal malignancies.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3864229 | PMC |
| http://dx.doi.org/10.1102/1470-7330.2013.0048 | DOI Listing |
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