AI Article Synopsis
- The study evaluates the incidence and challenges of virilization of external genitalia (VEG) in young girls in southeast Nigeria, highlighting issues like poor awareness and delayed diagnosis.
- The analyzed group consisted of 23 children, with various Prader types identified, and many being raised as male before gender assignment to female at a later age.
- Management outcomes revealed complications such as vaginal stenosis and surgical infections, pointing to the need for better healthcare education, resources, and funding to improve detection and treatment.
Article Abstract
Objective: Virilization of the external genitalia in young girls (VEG) manifests mostly as ambiguity of the genitalia and elicits concerns and uncertainties especially in settings with poor awareness. This study evaluates the profile and challenges of VEG in southeast Nigeria.
Methods: We analyzed 23 children with VEG managed in 2 referral centers in southeast Nigeria from June 2005 to January 2013.
Results: They presented at median age of 13.3 months (interquartile range [IQR] 3 months-3 years). The cases included 3 (13%) of Prader type 1, 6 (26%) of type 2, 11 (48%) of type 3, and 3 (13%) of type 4. Five of the Prader type 3 and all 3 cases of Prader type 4 were reared as male prior to presentation. Following evaluation, all the cases were assigned female gender at a mean age of 2.7 years (range 2 months-10.5 years). Appropriate feminizing genitoplasty was undertaken in all the cases and after a follow-up period of 3 months to 5 years (mean 2 years), 2 patients developed vaginal stenosis, and 3 cases had surgical wound infection. Poor awareness, delayed presentation, inadequate facilities, and lack of trained manpower were the challenges in the management of the cases.
Conclusion: VEG in our setting is associated with delayed management. Focused health education and public awareness programs, and improved healthcare funding may improve outcome and minimize the need for gender reassignment.
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| http://dx.doi.org/10.1016/j.jpag.2013.07.004 | DOI Listing |
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