Background: Delivery of a timely (within 24h) hepatitis B vaccine birth dose (TBD) is essential to prevent the long-term complications of hepatitis B virus (HBV) infection. China made substantial progress in hepatitis B immunization coverage, however, in 2004, TBD coverage was lower in Western, poorer provinces.
Methods: We reviewed five demonstration projects for the promotion of TBD in rural counties in Qinghai, Gansu and Ningxia. Interventions consisted of (1) work to increase TBD coverage in hospitals, including training of health-care workers, (2) information, education and communication [IEC] with the population and (3) micro-plans to deliver TBD for home births. We evaluated outcome through measuring TBD coverage for home and hospital births.
Results: These projects were implemented in the context of national efforts to promote institutional deliveries that lead to increases ranging from 10% to 17% to reach 43-97% proportion of institutional births at the end of the projects. Among institutional births, TBD coverage increased by 2% to 13% to reach post implementation coverage ranging from 98% to 100%. Among home births, TBD coverage increased by 7% to 56% to reach post implementation coverage ranging from 29% to 88%. Overall, TBD coverage increased by 4% to 36% to reach post implementation coverage ranging from 82% to 88%.
Conclusions: Demonstration projects based on combined interventions increased TBD coverage. Increases in institutional births amplified the results obtained. Use of standardized indicators for such projects would facilitate evaluation and identify intervention components that are most effective.
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http://dx.doi.org/10.1016/j.vaccine.2013.03.025 | DOI Listing |
Sci Data
February 2024
Water, Wetlands and Coasts Science, Environment and Heritage, Department of Climate Change, Energy, the Environment and Water, NSW Government, Lidcombe, Australia.
Wind wave observations in shallow coastal waters are essential for calibrating, validating, and improving numerical wave models to predict sediment transport, shoreline change, and coastal hazards such as beach erosion and oceanic inundation. Although ocean buoys and satellites provide near-global coverage of deep-water wave conditions, shallow-water wave observations remain sparse and often inaccessible. Nearshore wave conditions may vary considerably alongshore due to coastline orientation and shape, bathymetry and islands.
View Article and Find Full Text PDFClin Infect Dis
September 2023
Department of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Background: Tuberculosis infection (TBI) and TB disease (TBD) incidence remains poorly described following household contact (HHC) rifampin-/multidrug-resistant TB exposure. We sought to characterize TBI and TBD incidence at 1 year in HHCs and to evaluate TB preventive treatment (TPT) use in high-risk groups.
Methods: We previously conducted a cross-sectional study of HHCs with rifampin-/multidrug-resistant TB in 8 high-burden countries and reassessed TBI (interferon-gamma release assay, HHCs aged ≥5 years) and TBD (HHCs all ages) at 1 year.
Nat Biotechnol
February 2024
SNIPR BIOME ApS, Copenhagen, Denmark.
Antibiotic treatments have detrimental effects on the microbiome and lead to antibiotic resistance. To develop a phage therapy against a diverse range of clinically relevant Escherichia coli, we screened a library of 162 wild-type (WT) phages, identifying eight phages with broad coverage of E. coli, complementary binding to bacterial surface receptors, and the capability to stably carry inserted cargo.
View Article and Find Full Text PDFVaccine
June 2018
Department of Maternal and Child Health, School of Public Health, Peking University, Beijing, China. Electronic address:
Objective: To compare timely birth dose (TBD) coverage of hepatitis B vaccine and socio-economic inequality distribution of TBD coverage between 2011 and 2016 in rural areas of western China.
Methods: In western China, using multi-stage probability proportion to size sampling, 2633 and 1929 children aged 0-35 months with an immunization card were selected from 14 rural counties in 2011 and 2016, respectively. Socio-economic characteristics were obtained from face-to-face questionnaire survey and copies of vaccination certificates.
Vopr Kurortol Fizioter Lech Fiz Kult
March 2018
State budgetary educational institution of higher professional education 'I.I. Mechnikov North-Western State Medical University', Ministry of Health of the Russian Federation, Kirochnaya street 41, Saint-Petersburg, Russia, 191015.
The main statistical indicators of the activities of physiotherapy units (PTU) in the tuberculosis dispensaries (TBD) of Saint Petersburg are presented. Monitoring the compliance of the equipment available in PTU of TBD with the requirements of the modern Health Care Standard for the patients suffering from tuberculosis (TB) as approved by the Ministry of Health of the Russian Federation has been carried out. It has demonstrated that the current state of medical care in this country provides but the limited availability of the physiotherapeutic treatment for the TB patients.
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