The Gram-Negative 'Superbugs' Conference of the Australasian Society for Infectious Diseases, Gold Coast, Queensland, Australia, 2-3 August 2013 The Australian Society for Infectious Diseases hosted a national conference focused specifically on raising awareness of and contemplating solutions to the rise in antimicrobial resistance, especially in Gram-negative bacteria. Presentations were primarily informative, although some lively interactive sessions were held, particularly to debate contentious areas and to discuss options for policy makers and practitioners in infection control and antimicrobial stewardship. The conference brought together a diversity of backgrounds and interests, and was the first national meeting focused on this area.
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http://dx.doi.org/10.2217/fmb.13.144 | DOI Listing |
Pharmaceutics
January 2025
Division of Clinical Pharmacology, Department of Medicine, School of Medicine, The Johns Hopkins University, Baltimore, MD 21287, USA.
Long-acting and extended-release drug delivery strategies have greatly improved treatment for a variety of medical conditions. Special populations, specifically infants, children, young people, and pregnant and postpartum women, could greatly benefit from access to these strategies but are often excluded from clinical trials. We conducted a systematic review of all clinical studies involving the use of a long-acting intramuscular injection or implant in infants, children, young people, and pregnant and postpartum people.
View Article and Find Full Text PDFPathogens
January 2025
Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki 852-8523, Japan.
Information on circulating HBV (sub-)genotype, variants, and hepatitis D virus (HDV) coinfection, which vary by geographical area, is crucial for the efficient control and management of HBV. We investigated the genomic characteristics of HBV (with a prevalence of 8.1%) and the prevalence of HDV in Nigeria.
View Article and Find Full Text PDFPathogens
January 2025
Animal and Veterinary Research Centre (CECAV), Associate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), University of Trás-os-Montes e Alto Douro (UTAD), 5000-801 Vila Real, Portugal.
Wild birds may be involved in the transmission of agents of infectious diseases, including zoonoses, a circumstance which raises a number of public and animal health issues. Migratory bird species play a significant role in the introduction of tick-borne pathogens to new geographic areas, contributing to the dissemination of various etiological agents. This preliminary study aimed to assess the occurrence of four potentially zoonotic pathogens ( spp.
View Article and Find Full Text PDFPathogens
January 2025
Center for Infectious, Zoonotic and Vector-Borne Diseases, Lincoln Memorial University, Harrogate, TN 37752, USA.
According to the Humane Society, 25 to 40 percent of pet dogs in the United States are adopted from animal shelters. Shelter dogs can harbor bacterial, viral, fungal, and protozoal pathogens, posing risks to canine and human health. These bacterial pathogens may also carry antibiotic resistance genes (ARGs), serving as a reservoir for antimicrobial resistance (AMR) transmission.
View Article and Find Full Text PDFBiomolecules
December 2024
Department of Anatomy and Developmental Biology, Faculty of Medicine, Shimane University, 89-1 Enya-cho, Izumo 693-8501, Shimane, Japan.
The prognosis of spinal cord injury (SCI) is closely linked to secondary injury processes, predominantly driven by neuroinflammation. Interleukin-18 (IL-18) plays a pivotal role in this inflammatory response. In previous work, we developed an anti-IL-18 antibody capable of neutralizing the active form of IL-18.
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