AI Article Synopsis

  • Aortic knob calcification (AC) is linked to a higher risk of cardiovascular and cerebrovascular events, particularly in ischemic stroke patients with intracranial stenosis.
  • Researchers evaluated AC through routine chest X-rays in 307 stroke patients and found that those with AC were older and had a higher prevalence of intracranial stenosis.
  • The study concluded that AC is a significant predictor of intracranial stenosis, emphasizing its potential role in assessing stroke risk.

Article Abstract

Background And Purpose: Aortic knob calcification (AC) is associated with increased risks of cardiovascular and cerebrovascular events. We evaluated the clinical importance of AC in ischemic stroke patients with intracranial (IC) stenosis using simple, non-invasive and routine chest radiography.

Methods: The presence of AC was assessed in a chest posteroanterior view in 307 acute ischemic stroke patients admitted from May 2009 to April 2010, and who underwent magnetic resonance angiography or distal subtraction angiography. The association of AC with IC stenosis was analyzed.

Results: Patient age (68.3±8.7 vs. 65.9±8.27 years, P=0.04), and the prevalence of IC stenosis (70.7 vs. 41.3%, P<0.01) were higher in patients with AC than in patients without calcification. After adjusting for age, gender and vascular risk factors, logistic regression analysis showed that AC (Odds ratio, 3.54; 95% confidence interval, 1.90 to 6.61, P<0.01) and age (Odds ratio, 1.79; 95% confidence interval, 1.01 to 3.19; P=0.04) were independent factors affecting IC stenosis.

Conclusions: AC appears to be a reliable predictor for IC stenosis, an important mechanism of ischemic stroke.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779667PMC
http://dx.doi.org/10.5853/jos.2013.15.2.122DOI Listing

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