The study of 304 patients with chronic hepatitis C is presented. It was shown that in patients with chronic hepatitis C the occurrence and increase of violations of a functional condition of vegetative nervous system it is combined with emergence and progressing of signs of the mixed cryoglobulinemia. Clinical demonstration of the HCV associated crioglobulinemia syndrome is accompanied by the most expressed vegetative dysfunction, the being characterized low capacity of variability of a rhythm of heart and development of a vegetative disbalance and sympathicotonia.

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